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Acaa1b acetyl-Coenzyme A acyltransferase 1B [ Mus musculus (house mouse) ]

Gene ID: 235674, updated on 23-Jun-2021

Summary

Official Symbol
Acaa1bprovided by MGI
Official Full Name
acetyl-Coenzyme A acyltransferase 1Bprovided by MGI
Primary source
MGI:MGI:3605455
See related
Ensembl:ENSMUSG00000010651
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in liver adult (RPKM 383.0), kidney adult (RPKM 114.5) and 8 other tissues See more
Orthologs
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Genomic context

See Acaa1b in Genome Data Viewer
Location:
9; 9 F3
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (118977111..118986161, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (119148043..119157093, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (119057161..119066211, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene villin-like Neighboring gene predicted gene, 51697 Neighboring gene phospholipase C, delta 1 Neighboring gene deleted in lung and esophageal cancer 1 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide pseudogene Neighboring gene solute carrier family 22 (organic cation transporter), member 14

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC29978

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetate CoA-transferase activity ISO
Inferred from Sequence Orthology
more info
 
enables acetyl-CoA C-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acetyl-CoA C-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables acetyl-CoA C-acyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables acetyl-CoA C-myristoyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
 
enables palmitoyl-CoA oxidase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in bile acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in fatty acid beta-oxidation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phenylacetate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in very long-chain fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
3-ketoacyl-CoA thiolase B, peroxisomal
Names
acetyl-CoA acyltransferase B
beta-ketothiolase B
peroxisomal 3-oxoacyl-CoA thiolase B
NP_666342.1
XP_006512177.1
XP_006512179.1
XP_011241272.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146230.3NP_666342.1  3-ketoacyl-CoA thiolase B, peroxisomal precursor

    See identical proteins and their annotated locations for NP_666342.1

    Status: VALIDATED

    Source sequence(s)
    AC055818
    Consensus CDS
    CCDS23608.1
    UniProtKB/Swiss-Prot
    Q8VCH0
    UniProtKB/TrEMBL
    Q3UKM0
    Related
    ENSMUSP00000010795.5, ENSMUST00000010795.5
    Conserved Domains (2) summary
    PLN02287
    Location:1420
    PLN02287; 3-ketoacyl-CoA thiolase
    cd00751
    Location:39421
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    118977111..118986161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512114.2XP_006512177.1  3-ketoacyl-CoA thiolase B, peroxisomal isoform X2

    See identical proteins and their annotated locations for XP_006512177.1

    Conserved Domains (1) summary
    PLN02287
    Location:1268
    PLN02287; 3-ketoacyl-CoA thiolase
  2. XM_011242970.1XP_011241272.1  3-ketoacyl-CoA thiolase B, peroxisomal isoform X1

    Conserved Domains (1) summary
    PLN02287
    Location:23356
    PLN02287; 3-ketoacyl-CoA thiolase
  3. XM_006512116.5XP_006512179.1  3-ketoacyl-CoA thiolase B, peroxisomal isoform X3

    See identical proteins and their annotated locations for XP_006512179.1

    Conserved Domains (1) summary
    PLN02287
    Location:1209
    PLN02287; 3-ketoacyl-CoA thiolase
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