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Zfp454 zinc finger protein 454 [ Mus musculus (house mouse) ]

Gene ID: 237758, updated on 23-Jun-2021

Summary

Official Symbol
Zfp454provided by MGI
Official Full Name
zinc finger protein 454provided by MGI
Primary source
MGI:MGI:2679253
See related
Ensembl:ENSMUSG00000048728
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B230342N19
Expression
Biased expression in CNS E11.5 (RPKM 2.3), CNS E14 (RPKM 2.1) and 11 other tissues See more
Orthologs
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Genomic context

See Zfp454 in Genome Data Viewer
Location:
11; 11 B1.3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (50763545..50778463, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (50872718..50887634, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (50686224..50700945, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 879 Neighboring gene glutamate receptor, metabotropic 6 Neighboring gene zinc finger protein 2 Neighboring gene zinc finger protein 354B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Clone Names

  • MGC57560

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359531.1NP_001346460.1  zinc finger protein 454 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, uses an alternate start codon and lacks three coding exons, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK046117, BC049793
    Conserved Domains (2) summary
    COG5048
    Location:135447
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001382449.1NP_001369378.1  zinc finger protein 454 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (3) summary
    smart00349
    Location:1466
    KRAB; krueppel associated box
    COG5048
    Location:196531
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:343363
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001382450.1NP_001369379.1  zinc finger protein 454 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (3) summary
    smart00349
    Location:1466
    KRAB; krueppel associated box
    COG5048
    Location:196531
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:343363
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001382451.1NP_001369380.1  zinc finger protein 454 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Related
    ENSMUSP00000129125.2, ENSMUST00000163301.8
    Conserved Domains (3) summary
    smart00349
    Location:1467
    KRAB; krueppel associated box
    COG5048
    Location:197532
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:344364
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001382452.1NP_001369381.1  zinc finger protein 454 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (2) summary
    COG5048
    Location:163498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_001382453.1NP_001369382.1  zinc finger protein 454 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (2) summary
    COG5048
    Location:163498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_001382454.1NP_001369383.1  zinc finger protein 454 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (2) summary
    COG5048
    Location:133468
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. NM_001382455.1NP_001369384.1  zinc finger protein 454 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (2) summary
    COG5048
    Location:133468
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:280300
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. NM_001382456.1NP_001369385.1  zinc finger protein 454 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (2) summary
    COG5048
    Location:142477
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:289309
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. NM_001382457.1NP_001369386.1  zinc finger protein 454 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL627215
    Conserved Domains (2) summary
    COG5048
    Location:164499
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:311331
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. NM_172794.3NP_766382.2  zinc finger protein 454 isoform 1

    See identical proteins and their annotated locations for NP_766382.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK046117, BC049793
    Consensus CDS
    CCDS24639.1
    UniProtKB/TrEMBL
    Q80Y34
    Related
    ENSMUSP00000061824.7, ENSMUST00000050595.13
    Conserved Domains (3) summary
    smart00349
    Location:1467
    KRAB; krueppel associated box
    COG5048
    Location:197532
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:344364
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    50763545..50778463 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245962.2XP_030101822.1  zinc finger protein 454 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:135447
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:259279
    ZF_C2H2; C2H2 Zn finger [structural motif]
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