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Gas2l2 growth arrest-specific 2 like 2 [ Mus musculus (house mouse) ]

Gene ID: 237891, updated on 23-Jun-2021

Summary

Official Symbol
Gas2l2provided by MGI
Official Full Name
growth arrest-specific 2 like 2provided by MGI
Primary source
MGI:MGI:3652048
See related
Ensembl:ENSMUSG00000020686
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in ovary adult (RPKM 1.5), lung adult (RPKM 1.3) and 9 other tissues See more
Orthologs
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Genomic context

See Gas2l2 in Genome Data Viewer
Location:
11; 11 C
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83312461..83320347, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83421635..83429521, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (83235404..83242957, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene adaptor-related protein complex 2, beta 1 subunit Neighboring gene predicted gene, 23951 Neighboring gene RAS-like, family 10, member B Neighboring gene RIKEN cDNA 1700020L24 gene Neighboring gene matrix metallopeptidase 28 (epilysin) Neighboring gene TATA-box binding protein associated factor 15

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein alpha-subunit binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables actin filament binding ISO
Inferred from Sequence Orthology
more info
 
enables cytoskeletal anchor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cytoskeletal anchor activity ISO
Inferred from Sequence Orthology
more info
 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in actin filament IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with actin filament ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with ciliary basal body IMP
Inferred from Mutant Phenotype
more info
PubMed 
colocalizes_with ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with microtubule ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with microtubule plus-end IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with microtubule plus-end ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with stress fiber IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with stress fiber ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013759.2NP_001013781.1  GAS2-like protein 2

    See identical proteins and their annotated locations for NP_001013781.1

    Status: VALIDATED

    Source sequence(s)
    BB806501, BC147480
    Consensus CDS
    CCDS25164.1
    UniProtKB/Swiss-Prot
    Q5SSG4
    Related
    ENSMUSP00000051907.3, ENSMUST00000052521.9
    Conserved Domains (2) summary
    cd00014
    Location:34159
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam02187
    Location:207274
    GAS2; Growth-Arrest-Specific Protein 2 Domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    83312461..83320347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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