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Vash1 vasohibin 1 [ Mus musculus (house mouse) ]

Gene ID: 238328, updated on 7-Aug-2021

Summary

Official Symbol
Vash1provided by MGI
Official Full Name
vasohibin 1provided by MGI
Primary source
MGI:MGI:2442543
See related
Ensembl:ENSMUSG00000021256
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TTCP 1; AI834978; D930046M13Rik; G630009D10Rik
Expression
Broad expression in whole brain E14.5 (RPKM 15.3), CNS E14 (RPKM 13.4) and 16 other tissues See more
Orthologs
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Genomic context

See Vash1 in Genome Data Viewer
Location:
12; 12 D2
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (86725474..86742462)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (86678700..86695688)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (88019650..88036631)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene poly(rC) binding protein 2 pseudogene Neighboring gene predicted gene, 22004 Neighboring gene angel homolog 1 Neighboring gene pyruvate kinase, muscle pseudogene Neighboring gene predicted gene, 32755

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables actin binding ISO
Inferred from Sequence Orthology
more info
 
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metallocarboxypeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables metallocarboxypeptidase activity ISO
Inferred from Sequence Orthology
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within angiogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within labyrinthine layer blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of angiogenesis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in negative regulation of endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of lymphangiogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within placenta blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in proteolysis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in proteolysis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cellular senescence ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within response to wounding ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
located_in apical part of cell ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
tubulinyl-Tyr carboxypeptidase 1
Names
tyrosine carboxypeptidase 1
NP_796328.2
XP_011242409.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177354.4NP_796328.2  tubulinyl-Tyr carboxypeptidase 1

    See identical proteins and their annotated locations for NP_796328.2

    Status: VALIDATED

    Source sequence(s)
    AC102689
    Consensus CDS
    CCDS49118.1
    UniProtKB/Swiss-Prot
    Q8C1W1
    Related
    ENSMUSP00000021681.4, ENSMUST00000021681.4
    Conserved Domains (1) summary
    pfam14822
    Location:68312
    Vasohibin; Vasohibin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    86725474..86742462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244107.4XP_011242409.1  tubulinyl-Tyr carboxypeptidase 1 isoform X1

    See identical proteins and their annotated locations for XP_011242409.1

    Conserved Domains (1) summary
    pfam14822
    Location:1149
    Vasohibin
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