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Zfp367 zinc finger protein 367 [ Mus musculus (house mouse) ]

Gene ID: 238673, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp367provided by MGI
Official Full Name
zinc finger protein 367provided by MGI
Primary source
MGI:MGI:2442266
See related
Ensembl:ENSMUSG00000044934 AllianceGenome:MGI:2442266
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ZFF29a; ZFF29b; Znf367; 8030486J21Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Is expressed in several structures, including early conceptus; gonad; immune system; liver; and lung. Orthologous to human ZNF367 (zinc finger protein 367). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 9.6), liver E14.5 (RPKM 8.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
13 B3; 13 33.26 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (64280836..64301013, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (64133022..64153199, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene solute carrier family 35, member D2 Neighboring gene STARR-seq mESC enhancer starr_34820 Neighboring gene STARR-positive B cell enhancer ABC_E5404 Neighboring gene STARR-positive B cell enhancer ABC_E928 Neighboring gene STARR-positive B cell enhancer ABC_E7250 Neighboring gene hyaluronic acid binding protein 4 Neighboring gene CDC14 cell division cycle 14B Neighboring gene predicted gene, 46424

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of ZFF29: a protein containing a unique Cys2His2 zinc-finger motif. Asano H, et al. Biochem J, 2004 Dec 15. PMID 15344908, Free PMC Article
  2. Atypical E2F repressors and activators coordinate placental development. Ouseph MM, et al. Dev Cell, 2012 Apr 17. PMID 22516201, Free PMC Article
  3. Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Ulmke PA, et al. Stem Cell Reports, 2021 Apr 13. PMID 33798452, Free PMC Article
  4. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 367
Names
C2H2 zinc finger protein ZFF29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361047.1 → NP_001347976.1  zinc finger protein 367 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC158990, CT009717
    Conserved Domains (2) summary
    COG5048
    Location:43 → 116
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:45 → 65
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_175494.5 → NP_780703.1  zinc finger protein 367 isoform 1

    See identical proteins and their annotated locations for NP_780703.1

    Status: VALIDATED

    Source sequence(s)
    AC158990, CT009717
    Consensus CDS
    CCDS26596.1
    UniProtKB/Swiss-Prot
    B1B191, B1B192, Q0VDT2, Q8BH90, Q8BI44, Q8BI88
    Related
    ENSMUSP00000050854.5, ENSMUST00000059817.12
    Conserved Domains (2) summary
    COG5048
    Location:157 → 230
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:159 → 179
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    64280836..64301013 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VDT2.2 GenPept UniProtKB/Swiss-Prot:Q0VDT2

Gene LinkOut

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