Gapt Grb2-binding adaptor, transmembrane [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gaptprovided by MGI
Official Full Name: Grb2-binding adaptor, transmembraneprovided by MGI
Primary source: MGI:MGI:3608341
See related: Ensembl:ENSMUSG00000046006 AllianceGenome:MGI:3608341
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 9830130M13Rik
Summary: Acts upstream of or within B cell homeostasis and B cell proliferation involved in immune response. Predicted to be located in Golgi apparatus and plasma membrane. Orthologous to human GAPT (GRB2 binding adaptor protein, transmembrane). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in liver E18 (RPKM 2.1), spleen adult (RPKM 1.6) and 15 other tissues See more
Orthologs: human all
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Genomic context

Location:: 13 D2.1; 13 61.87 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (110489148..110493739, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (110352614..110357220, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2) 1 citation

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
acts_upstream_of_or_within B cell activation	IEA Inferred from Electronic Annotation more info
involved_in B cell homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within B cell homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in B cell proliferation involved in immune response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within B cell proliferation involved in immune response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in immunoglobulin production involved in immunoglobulin-mediated immune response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within immunoglobulin production involved in immunoglobulin-mediated immune response	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein GAPT

Names: growth factor receptor-bound protein 2-binding adapter protein, transmembrane

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.