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Lynx1 Ly6/neurotoxin 1 [ Mus musculus (house mouse) ]

Gene ID: 23936, updated on 23-Jun-2021

Summary

Official Symbol
Lynx1provided by MGI
Official Full Name
Ly6/neurotoxin 1provided by MGI
Primary source
MGI:MGI:1345180
See related
Ensembl:ENSMUSG00000022594
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SLURP-2; AI838844
Expression
Biased expression in cerebellum adult (RPKM 74.6), heart adult (RPKM 72.6) and 14 other tissues See more
Orthologs
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Genomic context

See Lynx1 in Genome Data Viewer
Location:
15; 15 D3
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (74619705..74624828, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (74747856..74752979, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (74578286..74583409, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33124 Neighboring gene secreted Ly6/Plaur domain containing 2 Neighboring gene lymphocyte antigen 6 complex, locus D Neighboring gene lymphocyte antigen 6 complex, locus G6G

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetylcholine receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables acetylcholine receptor inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables acetylcholine receptor inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acetylcholine receptor regulator activity ISO
Inferred from Sequence Orthology
more info
 
enables ion channel inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in anchored component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ly-6/neurotoxin-like protein 1
Names
GC26
secreted Ly-6/uPAR domain-containing protein 2
secreted Ly-6/uPAR-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011838.4NP_035968.1  ly-6/neurotoxin-like protein 1 precursor

    See identical proteins and their annotated locations for NP_035968.1

    Status: PROVISIONAL

    Source sequence(s)
    AC118022
    Consensus CDS
    CCDS27530.1
    UniProtKB/Swiss-Prot
    P0DP60
    Related
    ENSMUSP00000023259.9, ENSMUST00000023259.15
    Conserved Domains (1) summary
    cd00117
    Location:2194
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    74619705..74624828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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