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Zfp811 zinc finger protein 811 [ Mus musculus (house mouse) ]

Gene ID: 240063, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp811provided by MGI
Official Full Name
zinc finger protein 811provided by MGI
Primary source
MGI:MGI:2682944
See related
Ensembl:ENSMUSG00000055202 AllianceGenome:MGI:2682944
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in gut; nervous system; and neural retina. Orthologous to several human genes including ZNF44 (zinc finger protein 44); ZNF442 (zinc finger protein 442); and ZNF563 (zinc finger protein 563). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 8.3), CNS E14 (RPKM 8.0) and 7 other tissues See more
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Genomic context

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Location:
17 B1; 17 17.98 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33014650..33029033, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32795676..32810057, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 871 Neighboring gene STARR-positive B cell enhancer mm9_chr17:32925111-32925412 Neighboring gene predicted gene 17115 Neighboring gene predicted gene, 23294 Neighboring gene zinc finger protein 799 Neighboring gene zinc finger protein 458 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC62423

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 811

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001267583.1 → NP_001254512.1  zinc finger protein 811 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' region, which results in an early stop codon, compared to variant 1. The encoded isoform (2) has a shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AI413693, AK132056, BM951801, CT485613
    Consensus CDS
    CCDS89068.1
    UniProtKB/TrEMBL
    A0A3Q4EGT7
    Related
    ENSMUSP00000157159.2, ENSMUST00000234594.2
    Conserved Domains (2) summary
    smart00349
    Location:4 → 44
    KRAB; krueppel associated box
    pfam01352
    Location:4 → 43
    KRAB; KRAB box

  2. NM_183177.3 → NP_899000.2  zinc finger protein 811 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AI413693, AK132056, BC052046, CT485613
    Consensus CDS
    CCDS79528.1
    UniProtKB/TrEMBL
    A0A0J9YU71
    Related
    ENSMUSP00000144038.2, ENSMUST00000200914.5
    Conserved Domains (5) summary
    smart00349
    Location:4 → 44
    KRAB; krueppel associated box
    COG5048
    Location:217 → 547
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:279 → 299
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 43
    KRAB; KRAB box
    pfam13465
    Location:319 → 344
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    33014650..33029033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317470.3 → XP_017172959.1  zinc finger protein 811 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:208 → 357
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2 → 30
    KRAB; KRAB box

  2. XM_030249792.2 → XP_030105652.1  zinc finger protein 811 isoform X1

    Related
    ENSMUSP00000079709.7, ENSMUST00000080905.7
    Conserved Domains (3) summary
    COG5048
    Location:208 → 357
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2 → 30
    KRAB; KRAB box

  3. XM_011246439.3 → XP_011244741.1  zinc finger protein 811 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:206 → 355
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263 → 283
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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