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Zfp438 zinc finger protein 438 [ Mus musculus (house mouse) ]

Gene ID: 240186, updated on 23-Jun-2021

Summary

Official Symbol
Zfp438provided by MGI
Official Full Name
zinc finger protein 438provided by MGI
Primary source
MGI:MGI:2444919
See related
Ensembl:ENSMUSG00000050945
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9430031G09; 9430091M14Rik; B830013J05Rik
Expression
Broad expression in testis adult (RPKM 12.1), bladder adult (RPKM 1.5) and 17 other tissues See more
Orthologs
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Genomic context

See Zfp438 in Genome Data Viewer
Location:
18; 18 A1
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (5210027..5334826, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (5210027..5334826, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (5210029..5334437, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53196 Neighboring gene predicted gene, 26682 Neighboring gene predicted gene, 52372 Neighboring gene predicted gene, 34630

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360447.1NP_001347376.1  zinc finger protein 438

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC111128, AC133945
    Consensus CDS
    CCDS37721.1
    Related
    ENSMUSP00000156983.2, ENSMUST00000234241.2
    Conserved Domains (3) summary
    sd00017
    Location:495515
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:521543
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:507532
    zf-H2C2_2; Zinc-finger double domain
  2. NM_178722.5NP_848837.3  zinc finger protein 438

    See identical proteins and their annotated locations for NP_848837.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK034745, AK046812
    Consensus CDS
    CCDS37721.1
    UniProtKB/TrEMBL
    Q8BFX2, Q8BXJ4
    Related
    ENSMUSP00000067049.6, ENSMUST00000063989.7
    Conserved Domains (3) summary
    sd00017
    Location:495515
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:521543
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:507532
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    5210027..5334826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161137.1XP_036017030.1  zinc finger protein 438 isoform X2

    Conserved Domains (2) summary
    sd00017
    Location:430450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:456478
    zf-C2H2; Zinc finger, C2H2 type
  2. XM_011246916.2XP_011245218.1  zinc finger protein 438 isoform X1

    See identical proteins and their annotated locations for XP_011245218.1

    UniProtKB/TrEMBL
    Q8BFX2
    Conserved Domains (3) summary
    sd00017
    Location:495515
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:521543
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:507532
    zf-H2C2_2; Zinc-finger double domain
  3. XM_036161136.1XP_036017029.1  zinc finger protein 438 isoform X2

    Conserved Domains (2) summary
    sd00017
    Location:430450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:456478
    zf-C2H2; Zinc finger, C2H2 type
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