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Slco5a1 solute carrier organic anion transporter family, member 5A1 [ Mus musculus (house mouse) ]

Gene ID: 240726, updated on 5-Mar-2024

Summary

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Official Symbol
Slco5a1provided by MGI
Official Full Name
solute carrier organic anion transporter family, member 5A1provided by MGI
Primary source
MGI:MGI:2443431
See related
Ensembl:ENSMUSG00000025938 AllianceGenome:MGI:2443431
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4732454B15; A630033C23Rik
Summary
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; gonad; heart and pericardium; hemolymphoid system; and neural retina. Orthologous to human SLCO5A1 (solute carrier organic anion transporter family member 5A1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 5.0), CNS E14 (RPKM 4.2) and 12 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 A3; 1 3.71 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (12936773..13063043, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (12866549..12992796, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 17644 Neighboring gene sulfatase 1 Neighboring gene STARR-seq mESC enhancer starr_00233 Neighboring gene STARR-seq mESC enhancer starr_00244 Neighboring gene STARR-positive B cell enhancer ABC_E1989 Neighboring gene STARR-seq mESC enhancer starr_00248 Neighboring gene STARR-seq mESC enhancer starr_00251 Neighboring gene STARR-seq mESC enhancer starr_00254 Neighboring gene STARR-seq mESC enhancer starr_00260 Neighboring gene STARR-seq mESC enhancer starr_00263 Neighboring gene developmental pluripotency associated 5A pseudogene Neighboring gene predicted gene, 39592

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The zinc finger SET domain gene Prdm14 is overexpressed in lymphoblastic lymphomas with retroviral insertions at Evi32. Dettman EJ, et al. PLoS One, 2008. PMID 19043588, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
solute carrier organic anion transporter family member 5A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172841.2 → NP_766429.2  solute carrier organic anion transporter family member 5A1

    See identical proteins and their annotated locations for NP_766429.2

    Status: VALIDATED

    Source sequence(s)
    AC126044, AK041736, AV282837, AW490654, BQ031233
    Consensus CDS
    CCDS14821.2
    UniProtKB/TrEMBL
    E9PVD9
    Related
    ENSMUSP00000111062.3, ENSMUST00000115403.9
    Conserved Domains (1) summary
    cd17404
    Location:131 → 676
    MFS_SLCO5_OATP5; Solute carrier organic anion transporter 5 family of the Major Facilitator Superfamily of transporters

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    12936773..13063043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238382.4 → XP_011236684.1  solute carrier organic anion transporter family member 5A1 isoform X2

    Conserved Domains (1) summary
    cd17404
    Location:131 → 621
    MFS_SLCO5_OATP5; Solute carrier organic anion transporter 5 family of the Major Facilitator Superfamily of transporters

  2. XM_011238380.4 → XP_011236682.1  solute carrier organic anion transporter family member 5A1 isoform X1

    See identical proteins and their annotated locations for XP_011236682.1

    UniProtKB/TrEMBL
    E9PVD9
    Related
    ENSMUSP00000140091.2, ENSMUST00000188454.7
    Conserved Domains (1) summary
    cd17404
    Location:131 → 676
    MFS_SLCO5_OATP5; Solute carrier organic anion transporter 5 family of the Major Facilitator Superfamily of transporters

  3. XM_030253982.1 → XP_030109842.1  solute carrier organic anion transporter family member 5A1 isoform X3

    Conserved Domains (1) summary
    cl28910
    Location:33 → 276
    MFS; Major Facilitator Superfamily

  4. XM_006495518.4 → XP_006495581.1  solute carrier organic anion transporter family member 5A1 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:28 → 271
    MFS; Major Facilitator Superfamily

  5. XM_011238381.4 → XP_011236683.1  solute carrier organic anion transporter family member 5A1 isoform X1

    See identical proteins and their annotated locations for XP_011236683.1

    UniProtKB/TrEMBL
    E9PVD9
    Conserved Domains (1) summary
    cd17404
    Location:131 → 676
    MFS_SLCO5_OATP5; Solute carrier organic anion transporter 5 family of the Major Facilitator Superfamily of transporters

  6. XM_030253981.2 → XP_030109841.1  solute carrier organic anion transporter family member 5A1 isoform X2

    Conserved Domains (1) summary
    cd17404
    Location:131 → 621
    MFS_SLCO5_OATP5; Solute carrier organic anion transporter 5 family of the Major Facilitator Superfamily of transporters

  7. XM_030253983.2 → XP_030109843.1  solute carrier organic anion transporter family member 5A1 isoform X3

    Conserved Domains (1) summary
    cl28910
    Location:33 → 276
    MFS; Major Facilitator Superfamily

  8. XM_030253984.2 → XP_030109844.1  solute carrier organic anion transporter family member 5A1 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:28 → 271
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version

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