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Gpr161 G protein-coupled receptor 161 [ Mus musculus (house mouse) ]

Gene ID: 240888, updated on 23-Jun-2021

Summary

Official Symbol
Gpr161provided by MGI
Official Full Name
G protein-coupled receptor 161provided by MGI
Primary source
MGI:MGI:2685054
See related
Ensembl:ENSMUSG00000040836
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
vl; Gm208; Gm208Gpr
Expression
Biased expression in whole brain E14.5 (RPKM 9.4), CNS E18 (RPKM 9.0) and 14 other tissues See more
Orthologs
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Genomic context

See Gpr161 in Genome Data Viewer
Location:
1 H2.2; 1 72.64 cM
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (165108760..165154314)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (165281184..165326747)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (167225897..167251982)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene T-box 19 Neighboring gene SFT2 domain containing 2 Neighboring gene TIP41, TOR signalling pathway regulator-like (S. cerevisiae) Neighboring gene DDB1 and CUL4 associated factor 6 Neighboring gene predicted gene, 24637 Neighboring gene mitochondrial pyruvate carrier 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
vacuolated lens
GeneReviews: Not available

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in recycling endosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
G-protein coupled receptor 161

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081126.2NP_001074595.1  G-protein coupled receptor 161 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC116374, AK145635, BE991962, BY731738, CN721893
    UniProtKB/Swiss-Prot
    B2RPY5
    Conserved Domains (2) summary
    pfam00001
    Location:73353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:64270
    7tm_4; Olfactory receptor
  2. NM_001310429.1NP_001297358.1  G-protein coupled receptor 161 isoform 2

    See identical proteins and their annotated locations for NP_001297358.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC116374, BC137659, BE991962, BY731738, CN721893
    Consensus CDS
    CCDS83621.1
    UniProtKB/Swiss-Prot
    B2RPY5
    Related
    ENSMUSP00000136621.3, ENSMUST00000178700.8
    Conserved Domains (2) summary
    pfam00001
    Location:60340
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:51257
    7tm_4; Olfactory receptor
  3. NM_001310430.1NP_001297359.1  G-protein coupled receptor 161 isoform 3

    See identical proteins and their annotated locations for NP_001297359.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC116374, AK145635, BE991962
    Consensus CDS
    CCDS78732.1
    UniProtKB/Swiss-Prot
    B2RPY5
    UniProtKB/TrEMBL
    A0A140T8Q9
    Related
    ENSMUSP00000107077.3, ENSMUST00000111450.3
    Conserved Domains (1) summary
    cd15214
    Location:28334
    7tmA_GPR161; orphan G protein-coupled receptor 161, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    165108760..165154314
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496851.5XP_006496914.1  G-protein coupled receptor 161 isoform X1

    See identical proteins and their annotated locations for XP_006496914.1

    UniProtKB/Swiss-Prot
    B2RPY5
    UniProtKB/TrEMBL
    A0A140T8Q9
    Conserved Domains (1) summary
    cd15214
    Location:28334
    7tmA_GPR161; orphan G protein-coupled receptor 161, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. XM_011238821.4XP_011237123.1  G-protein coupled receptor 161 isoform X1

    See identical proteins and their annotated locations for XP_011237123.1

    UniProtKB/Swiss-Prot
    B2RPY5
    UniProtKB/TrEMBL
    A0A140T8Q9
    Conserved Domains (1) summary
    cd15214
    Location:28334
    7tmA_GPR161; orphan G protein-coupled receptor 161, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. XM_006496850.5XP_006496913.1  G-protein coupled receptor 161 isoform X1

    See identical proteins and their annotated locations for XP_006496913.1

    UniProtKB/Swiss-Prot
    B2RPY5
    UniProtKB/TrEMBL
    A0A140T8Q9
    Conserved Domains (1) summary
    cd15214
    Location:28334
    7tmA_GPR161; orphan G protein-coupled receptor 161, member of the class A family of seven-transmembrane G protein-coupled receptors
  4. XM_006496852.5XP_006496915.1  G-protein coupled receptor 161 isoform X1

    See identical proteins and their annotated locations for XP_006496915.1

    UniProtKB/Swiss-Prot
    B2RPY5
    UniProtKB/TrEMBL
    A0A140T8Q9
    Conserved Domains (1) summary
    cd15214
    Location:28334
    7tmA_GPR161; orphan G protein-coupled receptor 161, member of the class A family of seven-transmembrane G protein-coupled receptors
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