Vmn1r49 vomeronasal 1, receptor 49 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Vmn1r49provided by MGI
Official Full Name: vomeronasal 1, receptor 49provided by MGI
Primary source: MGI:MGI:1344384
See related: Ensembl:ENSMUSG00000095932 AllianceGenome:MGI:1344384
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: V1r5; VRi2; V1rb2
Summary: Predicted to enable signaling receptor activity. Predicted to act upstream of or within sensory perception of chemical stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Orthologous to several human genes including VN1R17P (vomeronasal 1 receptor 17 pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 6 D1; 6 40.02 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (90049068..90050000, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (90072086..90073018, complement)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

We show, in vivo, that the genetic replacement of the V1rb2 pheromone receptor coding sequence by an unrelated one from the odorant receptor gene M71 maintains gene exclusion, suggesting that a common mechanism is used to regulate their transcription.
Title: A common gene exclusion mechanism used by two chemosensory systems.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (4) 1 citation
Endonuclease-mediated (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:490596

NoName (e-PCR)
- UniSTS:493936

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables pheromone receptor activity	IEA Inferred from Electronic Annotation more info
enables signaling receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to pheromone	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sensory perception of chemical stimulus	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: vomeronasal type-1 receptor 49

Names: vomeronasal 1 receptor Vmn1r49; vomeronasal 1, receptor B2; vomeronasal organ family 1, receptor 5; vomeronasal organ family 1, receptor B2; vomeronasal receptor VRi2; vomeronasal type 1 receptor B2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.