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Xirp2 xin actin-binding repeat containing 2 [ Mus musculus (house mouse) ]

Gene ID: 241431, updated on 16-Oct-2021

Summary

Official Symbol
Xirp2provided by MGI
Official Full Name
xin actin-binding repeat containing 2provided by MGI
Primary source
MGI:MGI:2685198
See related
Ensembl:ENSMUSG00000027022
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Xin2; Cmya3; Gm352; AI452089; 2310003D02Rik; 2310008C07Rik; A530024P18Rik
Expression
Biased expression in heart adult (RPKM 8.8) and mammary gland adult (RPKM 2.5) See more
Orthologs
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Genomic context

See Xirp2 in Genome Data Viewer
Location:
2; 2 C1.3
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (67276343..67356964)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (67446000..67526620)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (67284059..67364663)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 13599 Neighboring gene predicted gene, 23328 Neighboring gene predicted gene 13601 Neighboring gene UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 Neighboring gene VISTA enhancer mm1717 Neighboring gene microRNA 7224

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables actin filament binding ISO
Inferred from Sequence Orthology
more info
 
enables alpha-actinin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cardiac muscle tissue morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell-cell junction organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ventricular septum development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Z disc IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
colocalizes_with focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with focal adhesion ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with stress fiber IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with stress fiber ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
xin actin-binding repeat-containing protein 2
Names
Xin actin-binding repeat containing 2 short splice form
beta-xin
cardiomyopathy associated 3
cardiomyopathy-associated protein 3
mXinbeta
myogenic MEF2-activated Xin-related protein
myomaxin
xeplin
xin-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024618.2NP_001019789.1  xin actin-binding repeat-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001019789.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ011666
    Consensus CDS
    CCDS16082.1
    UniProtKB/Swiss-Prot
    Q4U4S6
    Related
    ENSMUSP00000028410.4, ENSMUST00000028410.4
    Conserved Domains (3) summary
    cd09442
    Location:32573309
    LIM_Eplin_like; The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin) like proteins
    PTZ00423
    Location:22902391
    PTZ00423; glideosome-associated protein 45; Provisional
    pfam08043
    Location:862875
    Xin; Xin repeat
  2. NM_001083919.1NP_001077388.1  xin actin-binding repeat-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001077388.1

    Status: PROVISIONAL

    Source sequence(s)
    EF119716
    Consensus CDS
    CCDS38133.1
    UniProtKB/Swiss-Prot
    Q4U4S6
    Related
    ENSMUSP00000107966.2, ENSMUST00000112347.8
    Conserved Domains (2) summary
    PTZ00423
    Location:22902391
    PTZ00423; glideosome-associated protein 45; Provisional
    pfam08043
    Location:862875
    Xin; Xin repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    67276343..67356964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239520.2XP_011237822.1  xin actin-binding repeat-containing protein 2 isoform X1

    Conserved Domains (1) summary
    pfam08043
    Location:815830
    Xin; Xin repeat
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