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Rbm45 RNA binding motif protein 45 [ Mus musculus (house mouse) ]

Gene ID: 241490, updated on 23-Jun-2021

Summary

Official Symbol
Rbm45provided by MGI
Official Full Name
RNA binding motif protein 45provided by MGI
Primary source
MGI:MGI:2387367
See related
Ensembl:ENSMUSG00000042369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Drb; Drb1; Drbp1; G430095G15Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 13.8), CNS E14 (RPKM 13.6) and 28 other tissues See more
Orthologs
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Genomic context

See Rbm45 in Genome Data Viewer
Location:
2; 2 C3
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (76200304..76214112)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (76369959..76383768)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (76208041..76221825)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 11A Neighboring gene predicted gene, 52518 Neighboring gene cytochrome c, testis Neighboring gene oxysterol binding protein-like 6 Neighboring gene protein kinase, interferon inducible double stranded RNA dependent activator

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
RNA-binding protein 45
Names
RB-1
developmentally regulated RNA binding protein 1
dopamine receptor binding 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153405.2NP_700454.1  RNA-binding protein 45

    See identical proteins and their annotated locations for NP_700454.1

    Status: VALIDATED

    Source sequence(s)
    AK080420, AK140861, BB832413, CB597326
    Consensus CDS
    CCDS16157.1
    UniProtKB/Swiss-Prot
    Q8BHN5
    UniProtKB/TrEMBL
    Q3US38
    Related
    ENSMUSP00000040420.5, ENSMUST00000046389.5
    Conserved Domains (4) summary
    cd12366
    Location:23104
    RRM1_RBM45; RNA recognition motif 1 in RNA-binding protein 45 (RBM45) and similar proteins
    cd12367
    Location:120193
    RRM2_RBM45; RNA recognition motif 2 in RNA-binding protein 45 (RBM45) and similar proteins
    cd12368
    Location:248320
    RRM3_RBM45; RNA recognition motif 3 in RNA-binding protein 45 (RBM45) and similar proteins
    cd12369
    Location:393460
    RRM4_RBM45; RNA recognition motif 4 in RNA-binding protein 45 (RBM45) and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    76200304..76214112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003952822.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178090.2: Suppressed sequence

    Description
    NM_178090.2: This RefSeq was permanently suppressed because it contains a single nucleotide frameshift mutation that truncates the C-terminus of the protein and makes this transcript a candidate for nonsense-mediated mRNA decay (
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