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Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 [ Mus musculus (house mouse) ]

Gene ID: 243168, updated on 16-Oct-2021

Summary

Official Symbol
Hsd17b13provided by MGI
Official Full Name
hydroxysteroid (17-beta) dehydrogenase 13provided by MGI
Primary source
MGI:MGI:2140804
See related
Ensembl:ENSMUSG00000034528
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pan1b; AI047820; PAN1B-like
Expression
Biased expression in liver E18 (RPKM 99.4) and liver adult (RPKM 46.5) See more
Orthologs
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Genomic context

See Hsd17b13 in Genome Data Viewer
Location:
5; 5 E5
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (104103308..104125254, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (103955442..103977388, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (104384461..104406407, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene kelch-like 8 Neighboring gene predicted gene, 42139 Neighboring gene predicted gene, 24897 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 11 Neighboring gene microRNA 5619 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 9

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables steroid dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of lipid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in lipid droplet IDA
Inferred from Direct Assay
more info
PubMed 
located_in lipid droplet ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
17-beta-hydroxysteroid dehydrogenase 13
Names
17-beta-HSD 13
short-chain dehydrogenase/reductase 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163486.1NP_001156958.1  17-beta-hydroxysteroid dehydrogenase 13 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001156958.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (2).
    Source sequence(s)
    AI048624, AI573700, DV660487
    Consensus CDS
    CCDS51576.1
    UniProtKB/Swiss-Prot
    Q8VCR2
    Related
    ENSMUSP00000108422.3, ENSMUST00000112803.3
    Conserved Domains (2) summary
    cd05339
    Location:38277
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
    pfam00106
    Location:37228
    adh_short; short chain dehydrogenase
  2. NM_198030.2NP_932147.2  17-beta-hydroxysteroid dehydrogenase 13 isoform 2 precursor

    See identical proteins and their annotated locations for NP_932147.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate exon at its 3' terminus, compared to variant 1, which results in a protein (isoform 2) with a longer and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AI048624, AI573700, AL714024, DV660487
    Consensus CDS
    CCDS19480.1
    UniProtKB/Swiss-Prot
    Q8VCR2
    Related
    ENSMUSP00000046772.9, ENSMUST00000048118.15
    Conserved Domains (2) summary
    cd05339
    Location:38269
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
    pfam00106
    Location:37228
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    104103308..104125254 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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