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Defb15 defensin beta 15 [ Mus musculus (house mouse) ]

Gene ID: 246082, updated on 23-Jun-2021

Summary

Official Symbol
Defb15provided by MGI
Official Full Name
defensin beta 15provided by MGI
Primary source
MGI:MGI:2179202
See related
Ensembl:ENSMUSG00000048500
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BD-15
Expression
Restricted expression toward genital fat pad adult (RPKM 61.7) See more
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Genomic context

See Defb15 in Genome Data Viewer
Location:
8; 8 A2
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22419829..22422726, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (21929813..21932710, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (23040285..23043182, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene defensin beta 9 Neighboring gene defensin beta 11 Neighboring gene defensin beta 35 Neighboring gene predicted gene, 29821 Neighboring gene defensin beta 13

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables CCR2 chemokine receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables heparin binding ISO
Inferred from Sequence Orthology
more info
 
enables lipopolysaccharide binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in antifungal innate immune response ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within defense response IEA
Inferred from Electronic Annotation
more info
 
involved_in defense response to Gram-negative bacterium ISO
Inferred from Sequence Orthology
more info
 
involved_in defense response to Gram-positive bacterium ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extrinsic component of membrane ISO
Inferred from Sequence Orthology
more info
 
located_in microvesicle ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139222.3NP_631968.1  beta-defensin 15 precursor

    See identical proteins and their annotated locations for NP_631968.1

    Status: VALIDATED

    Source sequence(s)
    AJ437648
    Consensus CDS
    CCDS40288.1
    UniProtKB/Swiss-Prot
    Q8R2I5
    Related
    ENSMUSP00000059763.3, ENSMUST00000062586.3
    Conserved Domains (1) summary
    pfam13841
    Location:2554
    Defensin_beta_2; Beta defensin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    22419829..22422726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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