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metG methionine--tRNA ligase [ Palaeococcus pacificus DY20341 ]

Gene ID: 24841734, updated on 19-Dec-2022

Summary

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Gene symbol
metG
Gene description
methionine--tRNA ligase
Locus tag
PAP_RS03000
Gene type
protein coding
Organism
Palaeococcus pacificus DY20341 (strain: DY20341, culture-collection: DSM:24777, culture-collection: JCM:17873, type-material: type strain of Palaeococcus pacificus)
Lineage
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Palaeococcus
Old locus tag
PAP_03035
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Genomic context

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NZ_CP006019.1Genomic Context describing neighboring genes Neighboring gene Gar1/Naf1 family protein Neighboring gene transcription initiation factor IIB Neighboring gene ATP-dependent Clp protease proteolytic subunit Neighboring gene metalloregulator ArsR/SmtB family transcription factor

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP006019.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nakanishi K, et al. Nat Struct Mol Biol, 2005 Oct. PMID 16155581
  2. Selectivity and specificity of substrate binding in methionyl-tRNA synthetase. Datta D, et al. Protein Sci, 2004 Oct. PMID 15388861, Free PMC Article
  3. How methionyl-tRNA synthetase creates its amino acid recognition pocket upon L-methionine binding. Serre L, et al. J Mol Biol, 2001 Mar 2. PMID 11243794
  4. Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features. Mechulam Y, et al. J Mol Biol, 1999 Dec 17. PMID 10600385
  5. Mode of action and biochemical characterization of REP8839, a novel inhibitor of methionyl-tRNA synthetase. Ochsner UA, et al. Antimicrob Agents Chemother, 2005 Oct. PMID 16189106, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
methionine--tRNA ligase
WP_048164625.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP006019.1 Reference assembly

    Range
    522551..524641
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_048164625.1 methionine--tRNA ligase [Palaeococcus pacificus]

    See identical proteins and their annotated locations for WP_048164625.1

    UniProtKB/TrEMBL
    A0A075LSU0
    Conserved Domains (4) summary
    cd07957
    Location:384 → 511
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:2 → 375
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    PRK00133
    Location:1 → 695
    metG; methionyl-tRNA synthetase; Reviewed
    cd02800
    Location:592 → 696
    tRNA_bind_EcMetRS_like; tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine ...
Nucleotide Protein
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