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Npy5r neuropeptide Y receptor Y5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25340, updated on 6-May-2021

Summary

Official Symbol
Npy5rprovided by RGD
Official Full Name
neuropeptide Y receptor Y5provided by RGD
Primary source
RGD:3199
See related
Ensembl:ENSRNOG00000014172
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
NPYR5
Summary
receptor for neuropeptide Y and neuropeptide Y Y1; may be involved in regulation of energy homeostasis [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 14.9) See more
Orthologs
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Genomic context

See Npy5r in Genome Data Viewer
Location:
16p14
Exon count:
3
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (23055427..23063384)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (24796685..24805730)

Chromosome 16 - NC_051351.1Genomic Context describing neighboring genes Neighboring gene nuclear assembly factor 1 ribonucleoprotein Neighboring gene neuropeptide Y receptor Y1 Neighboring gene U7 small nuclear RNA Neighboring gene transketolase-like 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables neuropeptide Y receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables neuropeptide Y receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables pancreatic polypeptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables pancreatic polypeptide receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables pancreatic polypeptide receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables peptide YY receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptide YY receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables peptide YY receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in aging IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cardiac left ventricle morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within chemical synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
involved_in eating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in generation of ovulation cycle rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of acute inflammatory response to antigenic stimulus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of glutamate secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of synaptic transmission, GABAergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in outflow tract morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of ERK1 and ERK2 cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of acute inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of smooth muscle cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
neuropeptide Y receptor type 5
Names
NPY-Y5 receptor
NPY5-R
NPYY5-R
Neuropeptide Y5 receptor
Y5 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012869.2NP_037001.1  neuropeptide Y receptor type 5

    See identical proteins and their annotated locations for NP_037001.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000279
    UniProtKB/Swiss-Prot
    Q63634
    Related
    ENSRNOP00000018976.2, ENSRNOT00000018976.3
    Conserved Domains (2) summary
    pfam00001
    Location:58424
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:52170
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051351.1 Reference mRatBN7.2 Primary Assembly

    Range
    23055427..23063384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253014.4XP_006253076.1  neuropeptide Y receptor type 5 isoform X1

    See identical proteins and their annotated locations for XP_006253076.1

    UniProtKB/Swiss-Prot
    Q63634
    Conserved Domains (2) summary
    pfam00001
    Location:58424
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:52170
    7tm_4; Olfactory receptor
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