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lat1 putative dihydrolipoamide S-acetyltransferase E2 Lat1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538797, updated on 11-Apr-2024

Summary

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Gene symbol
lat1
Gene description
putative dihydrolipoamide S-acetyltransferase E2 Lat1
Primary source
PomBase:SPCC794.07
Locus tag
SPCC794.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003421.2 (262681..264770)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene putative TDT malic acid transporter Neighboring gene miscRNA Neighboring gene protein efr3 Neighboring gene translation elongation factor EF-1 alpha Ef1a-a Neighboring gene putative UTP-glucose-1-phosphate uridylyltransferase Neighboring gene putative ENTH/VHS domain-containing protein Ent3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article
  2. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article
  3. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Ren L, et al. PLoS One, 2011 Feb 28. PMID 21386897, Free PMC Article
  4. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
  5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables dihydrolipoyllysine-residue acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process from pyruvate IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in aerobic respiration IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion HDA PubMed 
part_of pyruvate dehydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative dihydrolipoamide S-acetyltransferase E2 Lat1
NP_587755.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    262681..264770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022748.2 → NP_587755.1  putative dihydrolipoamide S-acetyltransferase E2 Lat1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_587755.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O59816
    Conserved Domains (4) summary
    cd06849
    Location:54 → 127
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    TIGR01349
    Location:55 → 483
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form
    pfam00198
    Location:271 → 483
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:187 → 220
    E3_binding; e3 binding domain
Nucleotide Protein
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