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amk2 AMP-activated protein kinase beta subunit Amk2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539130, updated on 13-Mar-2024

Summary

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Gene symbol
amk2
Gene description
AMP-activated protein kinase beta subunit Amk2
Locus tag
SPCC1919.03c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003421.2 (2207485..2209022, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene putative nucleoside triphosphatase Neighboring gene putative nucleoside-triphosphatase Neighboring gene miscRNA Neighboring gene serine/threonine protein kinase Ppk34 Neighboring gene putative GPI synthesis protein pig-X Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene putative Ski complex TPR repeat subunit Ski3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural insight into AMPK regulation: ADP comes into play. Jin X, et al. Structure, 2007 Oct. PMID 17937917
  2. Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Townley R, et al. Science, 2007 Mar 23. PMID 17289942
  3. AMPK phosphorylation by Ssp1 is required for proper sexual differentiation in fission yeast. Valbuena N, et al. J Cell Sci, 2012 Jun 1. PMID 22375066
  4. A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability. Kriegenburg F, et al. PLoS Genet, 2014 Jan. PMID 24497846, Free PMC Article
  5. Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor. Hanyu Y, et al. Genes Cells, 2009 May. PMID 19371376

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase regulator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in CAMKK-AMPK signaling cascade IC
Inferred by Curator
more info
  
involved_in induction of conjugation with cellular fusion EXP
Inferred from Experiment
more info
 PubMed 
involved_in positive regulation of flocculation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
part_of nucleotide-activated protein kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nucleotide-activated protein kinase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
AMP-activated protein kinase beta subunit Amk2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2207485..2209022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023476.2 → NP_588485.1  AMP-activated protein kinase beta subunit Amk2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588485.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78789, Q1L851, Q9UU43
    Conserved Domains (2) summary
    smart01010
    Location:202 → 294
    AMPKBI; 5'-AMP-activated protein kinase beta subunit, interation domain
    pfam16561
    Location:100 → 180
    AMPK1_CBM; Glycogen recognition site of AMP-activated protein kinase
Nucleotide Protein
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