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pfk1 putative 6-phosphofructokinase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539972, updated on 7-Apr-2024

Summary

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Gene symbol
pfk1
Gene description
putative 6-phosphofructokinase
Primary source
PomBase:SPBC16H5.02
Locus tag
SPBC16H5.02
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2297164..2300512, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp7 Neighboring gene putative pho88 family protein Neighboring gene putative SUMO E1-like activator enzyme Fub2 Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene protein Sad1 Neighboring gene DNA polymerase delta subunit Cdm1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structures of S. pombe phosphofructokinase in the F6P-bound and ATP-bound states. Benjamin S, et al. J Struct Biol, 2007 Sep. PMID 17643314, Free PMC Article
  2. Purification, molecular and kinetic characterization of phosphofructokinase-1 from the yeast Schizosaccharomyces pombe: evidence for an unusual subunit composition. Reuter R, et al. Yeast, 2000 Oct. PMID 11015725
  3. The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2. Jongjitwimol J, et al. PLoS One, 2014. PMID 24818994, Free PMC Article
  4. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article
  5. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 6-phosphofructokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 6-phosphofructokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables AMP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables fructose-6-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fructose-6-phosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables monosaccharide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in canonical glycolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fructose 1,6-bisphosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fructose 1,6-bisphosphate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in fructose 6-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fructose 6-phosphate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glycolytic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructokinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of 6-phosphofructokinase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in cytoplasmic side of mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytosol HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative 6-phosphofructokinase
NP_595946.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2297164..2300512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021854.2 → NP_595946.1  putative 6-phosphofructokinase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595946.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42938, P78762
    Conserved Domains (2) summary
    TIGR02478
    Location:195 → 940
    6PF1K_euk; 6-phosphofructokinase, eukaryotic type
    cl00204
    Location:192 → 936
    PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...
Nucleotide Protein
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