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itr2 MFS myo-inositol transporter [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541827, updated on 15-Mar-2024

Summary

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Gene symbol
itr2
Gene description
MFS myo-inositol transporter
Locus tag
SPAC20G8.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1393608..1395820)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative DDHD family phospholipase Neighboring gene miscRNA Neighboring gene putative electron transfer flavoprotein-ubiquinone oxidoreductase Neighboring gene miscRNA Neighboring gene extended Fer/CIP4 (EFC) domain protein Cdc15 Neighboring gene putative CCR4-Not complex subunit Not1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Shizosaccharomyces pombe. Niederberger C, et al. Curr Genet, 1998 Apr. PMID 9560432
  2. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
  3. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables myo-inositol:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables myo-inositol:proton symporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables myo-inositol:proton symporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in myo-inositol import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in myo-inositol import across plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
MFS myo-inositol transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1393608..1395820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018751.2 → NP_593320.1  MFS myo-inositol transporter [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593320.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P78901, P87110
    Conserved Domains (2) summary
    cd06174
    Location:86 → 519
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:84 → 534
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein
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