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Crybb2 crystallin, beta B2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25422, updated on 13-Aug-2019

Summary

Official Symbol
Crybb2provided by RGD
Official Full Name
crystallin, beta B2provided by RGD
Primary source
RGD:2417
See related
Ensembl:ENSRNOG00000050023
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
structural protein of the lens of the eye; transiently expressed during development [RGD, Feb 2006]
Orthologs

Genomic context

See Crybb2 in Genome Data Viewer
Location:
12q16
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (49577580..49588555)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 12 NC_005111.3 (51351267..51361440)

Chromosome 12 - NC_005111.4Genomic Context describing neighboring genes Neighboring gene similar to hypothetical protein A530094D01 Neighboring gene uncharacterized LOC102552141 Neighboring gene crystallin, beta B3 Neighboring gene G protein-coupled receptor kinase 3 Neighboring gene myosin XVIIIb

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Wnt Signaling Pathway NetPath, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway NetPath, organism-specific biosystemWnt family of proteins are a large family of cysteine-rich secreted glycoproteins that regulate cell-cell interactions. They bind to members of the Frizzled family of 7 transmembrane receptors. Bindi...

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
identical protein binding ISO
Inferred from Sequence Orthology
more info
PubMed 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of eye lens IEA
Inferred from Electronic Annotation
more info
 
structural constituent of eye lens ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
camera-type eye development IEP
Inferred from Expression Pattern
more info
PubMed 
camera-type eye development ISO
Inferred from Sequence Orthology
more info
PubMed 
lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
visual perception IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
visual perception IEA
Inferred from Electronic Annotation
more info
 
visual perception ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
beta-crystallin B2
Names
R.norvegicus CRYBB2 gene (crystallin, beta B2)
beta-B2 crystallin
beta-crystallin Bp

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012937.1NP_037069.1  beta-crystallin B2

    See identical proteins and their annotated locations for NP_037069.1

    Status: PROVISIONAL

    Source sequence(s)
    X16072
    UniProtKB/Swiss-Prot
    P62697
    Related
    ENSRNOP00000067708.1, ENSRNOT00000072683.1
    Conserved Domains (1) summary
    pfam00030
    Location:108190
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005111.4 Reference Rnor_6.0 Primary Assembly

    Range
    49577580..49588555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017598273.1XP_017453762.1  beta-crystallin B2 isoform X1

    UniProtKB/Swiss-Prot
    P62697
    Conserved Domains (1) summary
    pfam00030
    Location:108190
    Crystall; Beta/Gamma crystallin

Alternate Rn_Celera

Genomic

  1. AC_000080.1 Alternate Rn_Celera

    Range
    45165513..45175496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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