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cdc42 Rho family GTPase Cdc42 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543027, updated on 22-Sep-2022

Summary

Gene symbol
cdc42
Gene description
Rho family GTPase Cdc42
Locus tag
SPAC110.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

See cdc42 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (1916054..1917656)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative serine/threonine protein kinase Ppk1 Neighboring gene cohesin-associated protein Pds5 Neighboring gene miscRNA Neighboring gene heat shock protein Pss1 Neighboring gene miscRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the cdc42 gene: The cdc42 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, M.oryzae, N.crassa, rice, and frog.

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTP binding ISM
Inferred from Sequence Model
more info
 
enables GTPase activity EXP
Inferred from Experiment
more info
PubMed 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein serine/threonine kinase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables signaling adaptor activity EXP
Inferred from Experiment
more info
PubMed 
Process Evidence Code Pubs
involved_in Cdc42 protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in bipolar cell growth EXP
Inferred from Experiment
more info
PubMed 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in establishment or maintenance of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in establishment or maintenance of cell polarity regulating cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic nuclear membrane biogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of mating projection assembly EXP
Inferred from Experiment
more info
PubMed 
involved_in positive regulation of mating projection assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of beta-glucan biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of division septum assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of endocytic recycling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of establishment or maintenance of cell polarity regulating cell shape EXP
Inferred from Experiment
more info
PubMed 
involved_in regulation of establishment or maintenance of cell polarity regulating cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of exocytosis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of exocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1916054..1917656
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018970.2NP_593536.1  Rho family GTPase Cdc42 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593536.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q01112
    Conserved Domains (2) summary
    smart00174
    Location:6179
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    cd01874
    Location:3177
    Cdc42; cell division cycle 42 (Cdc42) is a small GTPase of the Rho family