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ypt2 GTPase Ypt2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543280, updated on 11-Apr-2024

Summary

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Gene symbol
ypt2
Gene description
GTPase Ypt2
Locus tag
SPAC9E9.07c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4447723..4449571, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative bcap family protein Neighboring gene uncharacterized protein Neighboring gene putative threonine synthase Neighboring gene ATR checkpoint kinase regulatory subunit Rad26 Neighboring gene putative aldehyde dehydrogenase Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Function of the ypt2 gene in the exocytic pathway of Schizosaccharomyces pombe. Craighead MW, et al. Mol Biol Cell, 1993 Oct. PMID 8298192, Free PMC Article
  2. Structural and functional analysis of ypt2, an essential ras-related gene in the fission yeast Schizosaccharomyces pombe encoding a Sec4 protein homologue. Haubruck H, et al. EMBO J, 1990 Jun. PMID 2112089, Free PMC Article
  3. Meiosis-specific localization of the exocytic Rab Ypt2 in fission yeast. Imada K, et al. Small GTPases, 2020 Mar. PMID 28876998, Free PMC Article
  4. Identification of ras-related, YPT family genes in Schizosaccharomyces pombe. Miyake S, et al. EMBO J, 1990 May. PMID 2328721, Free PMC Article
  5. A guaninine nucleotide exchange factor is a component of the meiotic spindle pole body in Schizosaccharomyces pombe. Yang HJ, et al. Mol Biol Cell, 2010 Apr 1. PMID 20130084, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Meiosis-specific localization of the exocytic Rab Ypt2 in fission yeast.
    Title: Meiosis-specific localization of the exocytic Rab Ypt2 in fission yeast.
  2. SpSpo13 binds preferentially to the nucleotide-free form of ScSec4 and facilitates nucleotide exchange in vitro; SpYpt2 is the physiological substrate of SpSpo13 [Spo13]
    Title: A guaninine nucleotide exchange factor is a component of the meiotic spindle pole body in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Golgi to plasma membrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in Golgi vesicle fusion to target membrane IEA
Inferred from Electronic Annotation
more info
  
involved_in endocytic recycling IEA
Inferred from Electronic Annotation
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport IC
Inferred by Curator
more info
 PubMed 
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
  
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of exocytosis IEA
Inferred from Electronic Annotation
more info
  
involved_in signaling NAS
Non-traceable Author Statement
more info
  
involved_in vesicle docking involved in exocytosis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in meiotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in prospore membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in trans-Golgi network transport vesicle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GTPase Ypt2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4447723..4449571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020009.2 → NP_594580.1  GTPase Ypt2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594580.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P17609
    Conserved Domains (2) summary
    cd01867
    Location:7 → 173
    Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)
    pfam00071
    Location:11 → 172
    Ras; Ras family
Nucleotide Protein
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