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Slc34a1 solute carrier family 34 member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25548, updated on 6-May-2021

Summary

Official Symbol
Slc34a1provided by RGD
Official Full Name
solute carrier family 34 member 1provided by RGD
Primary source
RGD:3708
See related
Ensembl:ENSRNOG00000015262
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Npt2; NaPi-2; NaPi2A; Slc17a2
Summary
membrane carrier protein that may be involved with active transport of phosphate into cells via sodium cotransport [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 4338.1) See more
Orthologs
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Genomic context

See Slc34a1 in Genome Data Viewer
Location:
17p14
Exon count:
13
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9218876..9233852, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9747766..9762739, complement)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene coagulation factor XII Neighboring gene profilin 3 Neighboring gene U6 spliceosomal RNA Neighboring gene regulator of G-protein signaling 14

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables PDZ domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sodium:phosphate symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables sodium:phosphate symporter activity ISO
Inferred from Sequence Orthology
more info
 
enables sodium:phosphate symporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in arsenate ion transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within bone remodeling ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular phosphate ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to metal ion IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to parathyroid hormone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to staurosporine IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in dentinogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in gentamycin metabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in glycoprotein metabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in indole metabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in kidney development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in ossification IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in phosphate ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in phosphate ion transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in phosphate ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of membrane potential IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of phosphate transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of sodium-dependent phosphate transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of sodium-dependent phosphate transport IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in positive regulation of sodium-dependent phosphate transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to cadmium ion ISO
Inferred from Sequence Orthology
more info
 
involved_in response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to growth hormone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to lead ion ISO
Inferred from Sequence Orthology
more info
 
involved_in response to magnesium ion IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to mercury ion ISO
Inferred from Sequence Orthology
more info
 
involved_in response to nutrient IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to parathyroid hormone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to peptide IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to peptide hormone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to potassium ion IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to thyroid hormone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to vitamin A IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in sodium ion import across plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
involved_in sodium-dependent phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sodium-dependent phosphate transport IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in tricarboxylic acid metabolic process IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in brush border IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in brush border membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intrinsic component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitotic spindle IEA
Inferred from Electronic Annotation
more info
 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sodium-dependent phosphate transport protein 2A
Names
Na(+)-dependent phosphate cotransporter 2A
Na(+)/Pi cotransporter 2A
naPi-2a
sodium-phosphate co-transporter type II
sodium-phosphate transport protein 2A
sodium/phosphate cotransporter 2A
solute carrier family 17 (sodium/hydrogen exchanger) member 2
solute carrier family 34 (sodium phosphate), member 1
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013030.2NP_037162.1  sodium-dependent phosphate transport protein 2A

    See identical proteins and their annotated locations for NP_037162.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000284
    UniProtKB/Swiss-Prot
    Q06496
    Related
    ENSRNOP00000031764.4, ENSRNOT00000033749.5
    Conserved Domains (2) summary
    TIGR01013
    Location:108588
    2a58; Phosphate:Na+ Symporter (PNaS) Family
    pfam02690
    Location:113204
    Na_Pi_cotrans; Na+/Pi-cotransporter

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    9218876..9233852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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