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RAI14 retinoic acid induced 14 [ Homo sapiens (human) ]

Gene ID: 26064, updated on 7-Apr-2024

Summary

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Official Symbol
RAI14provided by HGNC
Official Full Name
retinoic acid induced 14provided by HGNC
Primary source
HGNC:HGNC:14873
See related
Ensembl:ENSG00000039560 MIM:606586; AllianceGenome:HGNC:14873
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RAI13; NORPEG
Summary
Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in endometrium (RPKM 27.5), placenta (RPKM 14.1) and 23 other tissues See more
Orthologs
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Genomic context

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Location:
5p13.2
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (34656328..34832612)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (34903424..35079712)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (34656433..34832717)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374721 Neighboring gene Sharpr-MPRA regulatory region 6534 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:34621050-34621410 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15966 Neighboring gene RAI14 divergent transcript Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34700297-34700798 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34700799-34701298 Neighboring gene uncharacterized LOC124900960 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34721500-34722000 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34722001-34722501 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:34735806-34736306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:34736307-34736807 Neighboring gene NANOG hESC enhancer GRCh37_chr5:34736814-34737353 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22465 Neighboring gene MPRA-validated peak5222 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22466 Neighboring gene uncharacterized LOC124900959 Neighboring gene TTC23L antisense RNA 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:34866693-34867892 Neighboring gene tetratricopeptide repeat domain 23 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners. Zhang R, et al. Mol Cell Proteomics, 2023 May. PMID 36934880, Free PMC Article
  2. The dual-crosslinked prospective values of RAI14 for the diagnosis and chemosurveillance in triple negative breast cancer. Cui R, et al. Ann Med, 2023 Dec. PMID 36880986, Free PMC Article
  3. RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway. Xu J, et al. Int J Mol Sci, 2022 Oct 10. PMID 36233342, Free PMC Article
  4. High Expression of Retinoic Acid Induced 14 (RAI14) in Gastric Cancer and Its Prognostic Value. He XY, et al. Med Sci Monit, 2018 Apr 14. PMID 29654694, Free PMC Article
  5. Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein. Kutty RK, et al. Biochem Biophys Res Commun, 2006 Jul 14. PMID 16729964

See all (111) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
    Title: Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
  2. The dual-crosslinked prospective values of RAI14 for the diagnosis and chemosurveillance in triple negative breast cancer.
    Title: The dual-crosslinked prospective values of RAI14 for the diagnosis and chemosurveillance in triple negative breast cancer.
  3. The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability.
    Title: The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability.
  4. RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
    Title: RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
  5. These findings provide significant insight into the role of RAI14 in mTOR-induced glial inflammation, which is closely associated with infection and ischemia stimuli.
    Title: Retinoic Acid-Induced Protein 14 (RAI14) Promotes mTOR-Mediated Inflammation Under Inflammatory Stress and Chemical Hypoxia in a U87 Glioblastoma Cell Line.
  6. TCGA database and Kaplan-Meier Plotter mining results showed that compared to those with RAI14 low mRNA expression levels, Gastric Cancer patients with RAI14 high mRNA expression levels had remarkably lower time of both overall survival and disease-free survival. Cox multivariate survival analyses shows high expression of RAI14 was the only independent predictor of unfavorable prognosis in patients with gastric cancer.
    Title: High Expression of Retinoic Acid Induced 14 (RAI14) in Gastric Cancer and Its Prognostic Value.
  7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  8. Subcellular localization of NORPEG in retinal pigment epithelial (ARPE-19) cells varies with cell density, with predominantly nuclear localization in nonconfluent cells, but a cytoplasmic localization in confluent cultures.
    Title: Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA1334, DKFZp564G013

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in fibrillar center IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankycorbin
Names
ankyrin repeat and coiled-coil structure-containing protein
novel retinal pigment epithelial cell protein
retinoic acid-induced protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145520.1 → NP_001138992.1  ankycorbin isoform a

    See identical proteins and their annotated locations for NP_001138992.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same isoform (a).
    Source sequence(s)
    AB037755, AF155135, AY317139
    Consensus CDS
    CCDS34142.1
    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Related
    ENSP00000388725.2, ENST00000428746.6
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  2. NM_001145521.2 → NP_001138993.1  ankycorbin isoform a

    See identical proteins and their annotated locations for NP_001138993.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same isoform (a).
    Source sequence(s)
    AF155135, AK308306, AY317139, BC028681, DB036130
    Consensus CDS
    CCDS34142.1
    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Related
    ENSP00000422942.1, ENST00000503673.5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  3. NM_001145522.2 → NP_001138994.1  ankycorbin isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.
    Source sequence(s)
    AF155135, AK314379, DA485361, DN994273
    Consensus CDS
    CCDS54837.1
    UniProtKB/Swiss-Prot
    Q9P0K7
    Related
    ENSP00000422377.1, ENST00000512629.5
    Conserved Domains (4) summary
    PHA03095
    Location:12 → 224
    PHA03095; ankyrin-like protein; Provisional
    PRK03918
    Location:401 → 917
    PRK03918; DNA double-strand break repair ATPase Rad50
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

  4. NM_001145523.2 → NP_001138995.1  ankycorbin isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, uses an alternate 5' coding exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    AF155135, AY317139, AY354204
    Consensus CDS
    CCDS54838.1
    UniProtKB/Swiss-Prot
    Q9P0K7
    Related
    ENSP00000423854.1, ENST00000506376.1
    Conserved Domains (4) summary
    PHA03095
    Location:3 → 216
    PHA03095; ankyrin-like protein; Provisional
    PRK03918
    Location:422 → 938
    PRK03918; DNA double-strand break repair ATPase Rad50
    sd00045
    Location:110 → 141
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:82 → 174
    Ank_2; Ankyrin repeats (3 copies)

  5. NM_001145525.2 → NP_001138997.1  ankycorbin isoform d

    See identical proteins and their annotated locations for NP_001138997.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, uses an alternate 5' coding exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (d) has a distinct N-terminus and is longer than isoform a.
    Source sequence(s)
    AF155135, AK308306, AY317139, DB036130
    Consensus CDS
    CCDS54839.1
    UniProtKB/Swiss-Prot
    Q9P0K7
    Related
    ENSP00000427123.1, ENST00000515799.5
    Conserved Domains (7) summary
    PRK03918
    Location:433 → 949
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:84 → 208
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:126 → 218
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:26 → 76
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:121 → 152
    ANK; ANK repeat [structural motif]
    cl03075
    Location:605 → 735
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:592 → 665
    DUF342; Protein of unknown function (DUF342)

  6. NM_015577.3 → NP_056392.2  ankycorbin isoform a

    See identical proteins and their annotated locations for NP_056392.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the predominant isoform (a). Variants 1-3 encode the same isoform (a).
    Source sequence(s)
    AF155135, BC028681, DA485361
    Consensus CDS
    CCDS34142.1
    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Related
    ENSP00000265109.3, ENST00000265109.8
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    34656328..34832612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047417088.1 → XP_047273044.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  2. XM_047417092.1 → XP_047273048.1  ankycorbin isoform X6

    Conserved Domains (4) summary
    PHA03095
    Location:12 → 224
    PHA03095; ankyrin-like protein; Provisional
    PRK03918
    Location:401 → 917
    PRK03918; DNA double-strand break repair ATPase Rad50
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_017009335.2 → XP_016864824.1  ankycorbin isoform X6

    UniProtKB/Swiss-Prot
    Q9P0K7
    Conserved Domains (4) summary
    PHA03095
    Location:12 → 224
    PHA03095; ankyrin-like protein; Provisional
    PRK03918
    Location:401 → 917
    PRK03918; DNA double-strand break repair ATPase Rad50
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_011514021.3 → XP_011512323.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_011512323.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  5. XM_047417091.1 → XP_047273047.1  ankycorbin isoform X6

    Conserved Domains (4) summary
    PHA03095
    Location:12 → 224
    PHA03095; ankyrin-like protein; Provisional
    PRK03918
    Location:401 → 917
    PRK03918; DNA double-strand break repair ATPase Rad50
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_011514017.3 → XP_011512319.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_011512319.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  7. XM_011514019.2 → XP_011512321.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_011512321.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  8. XM_011514020.2 → XP_011512322.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_011512322.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  9. XM_011514018.2 → XP_011512320.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_011512320.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  10. XM_047417089.1 → XP_047273045.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  11. XM_006714469.3 → XP_006714532.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_006714532.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  12. XM_011514022.2 → XP_011512324.1  ankycorbin isoform X2

    See identical proteins and their annotated locations for XP_011512324.1

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
    Conserved Domains (7) summary
    PRK03918
    Location:430 → 946
    PRK03918; chromosome segregation protein; Provisional
    cd00204
    Location:81 → 205
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:123 → 215
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:23 → 73
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:118 → 149
    ANK; ANK repeat [structural motif]
    cl03075
    Location:602 → 732
    GrpE; nucleotide exchange factor GrpE
    cl19219
    Location:589 → 662
    DUF342; Protein of unknown function (DUF342)

  13. XM_047417090.1 → XP_047273046.1  ankycorbin isoform X5

  14. XM_024446017.2 → XP_024301785.1  ankycorbin isoform X3

    Conserved Domains (5) summary
    cd00204
    Location:73 → 197
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:110 → 141
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:181 → 240
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:27 → 85
    Ank_5; Ankyrin repeats (many copies)
    cl25732
    Location:422 → 938
    SMC_N; RecF/RecN/SMC N terminal domain

  15. XM_011514016.3 → XP_011512318.2  ankycorbin isoform X1

  16. XM_011514025.3 → XP_011512327.2  ankycorbin isoform X4

  17. XM_047417093.1 → XP_047273049.1  ankycorbin isoform X7

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    34903424..35079712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054352339.1 → XP_054208314.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  2. XM_054352354.1 → XP_054208329.1  ankycorbin isoform X6

  3. XM_054352352.1 → XP_054208327.1  ankycorbin isoform X6

  4. XM_054352346.1 → XP_054208321.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  5. XM_054352353.1 → XP_054208328.1  ankycorbin isoform X6

  6. XM_054352340.1 → XP_054208315.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  7. XM_054352345.1 → XP_054208320.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  8. XM_054352344.1 → XP_054208319.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  9. XM_054352343.1 → XP_054208318.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  10. XM_054352341.1 → XP_054208316.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  11. XM_054352347.1 → XP_054208322.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  12. XM_054352342.1 → XP_054208317.1  ankycorbin isoform X2

    UniProtKB/Swiss-Prot
    E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

  13. XM_054352338.1 → XP_054208313.1  ankycorbin isoform X8

  14. XM_054352351.1 → XP_054208326.1  ankycorbin isoform X5

  15. XM_054352348.1 → XP_054208323.1  ankycorbin isoform X1

  16. XM_054352349.1 → XP_054208324.1  ankycorbin isoform X3

  17. XM_054352350.1 → XP_054208325.1  ankycorbin isoform X4

  18. XM_054352355.1 → XP_054208330.1  ankycorbin isoform X7

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9P0K7.2 GenPept UniProtKB/Swiss-Prot:Q9P0K7

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