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SdicC Sperm-specific dynein intermediate chain C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 26067076, updated on 27-Feb-2024

Summary

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Official Symbol
SdicCprovided by FlyBase
Official Full Name
Sperm-specific dynein intermediate chain Cprovided by FlyBase
Primary source
FLYBASE:FBgn0283434
Locus tag
Dmel_CG46277
See related
AllianceGenome:FB:FBgn0283434
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG46277; Dmel\CG46277
Summary
Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in transport along microtubule. Predicted to be part of cytoplasmic dynein complex. Orthologous to human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
19C1-19C1; 1-64 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20212738..20217259, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Sperm-specific dynein intermediate chain B Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Sperm-specific dynein intermediate chain 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004354.4 Chromosome X Reference Release 6 plus ISO1 MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rapid Functional and Sequence Differentiation of a Tandemly Repeated Species-Specific Multigene Family in Drosophila. Clifton BD, et al. Mol Biol Evol, 2017 Jan. PMID 27702774, Free PMC Article
  2. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100
  3. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article
  4. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867, Free PMC Article
  5. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables dynein heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dynein light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
  
involved_in transport along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of cytoplasmic dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytoplasmic dynein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sperm-specific dynein intermediate chain C
Names
CG46277-PA
SdicC-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    20212738..20217259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001316649.1 → NP_001303578.1  Sperm-specific dynein intermediate chain C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BHW5, T2FGB0
    Conserved Domains (5) summary
    COG2319
    Location:224 → 534
    WD40; WD40 repeat [General function prediction only]
    COG2811
    Location:108 → 178
    NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
    pfam11540
    Location:23 → 51
    Dynein_IC2; Cytoplasmic dynein 1 intermediate chain 2
    sd00039
    Location:196 → 245
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:196 → 523
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
T2FGB0 T2FGB0

Gene LinkOut

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