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Ceacam10 CEA cell adhesion molecule 10 [ Mus musculus (house mouse) ]

Gene ID: 26366, updated on 16-Apr-2024

Summary

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Official Symbol
Ceacam10provided by MGI
Official Full Name
CEA cell adhesion molecule 10provided by MGI
Primary source
MGI:MGI:1347248
See related
Ensembl:ENSMUSG00000054169 AllianceGenome:MGI:1347248
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bgp3; Cea10
Summary
Acts upstream of or within flagellated sperm motility. Located in extracellular region. Is expressed in alimentary system; immune system; and reproductive system. Orthologous to several human genes including CEACAM4 (CEA cell adhesion molecule 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in genital fat pad adult (RPKM 164.8), colon adult (RPKM 46.0) and 3 other tissues See more
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Genomic context

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Location:
7 A3; 7 12.78 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (24476592..24484081)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24777167..24784656)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18276 Neighboring gene Ly6/PLAUR domain containing 11 Neighboring gene CD177 antigen Neighboring gene STARR-seq mESC enhancer starr_18277 Neighboring gene STARR-seq mESC enhancer starr_18278 Neighboring gene predicted gene 5893 Neighboring gene STARR-seq mESC enhancer starr_18280 Neighboring gene predicted gene, 38965

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Demonstration of a glycoprotein derived from the Ceacam10 gene in mouse seminal vesicle secretions. Li SH, et al. Biol Reprod, 2005 Sep. PMID 15901639, Free PMC Article
  2. A carcinoembryonic antigen family cDNA from mouse placenta encoding a protein with a rare domain composition. Kataoka K, et al. Placenta, 2000 Sep. PMID 10985962
  3. Increased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1. Heckt T, et al. PLoS One, 2014. PMID 25490771, Free PMC Article
  4. The cea10 gene encodes a secreted member of the murine carcinoembryonic antigen family and is expressed in the placenta, gastrointestinal tract and bone marrow. Keck U, et al. Eur J Biochem, 1995 Apr 15. PMID 7744068
  5. Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development. Finkenzeller D, et al. Mol Cell Biol, 2003 Jan. PMID 12482980, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The purification and physiological role of CEACAM10 in male mice is reported. [CEACAM]
    Title: Demonstration of a glycoprotein derived from the Ceacam10 gene in mouse seminal vesicle secretions.
  2. Taken together, both Ceacam10 and Ceacam9, alone or in combination, are not essential for either murine placental and embryonic development or for adult life.
    Title: Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein tyrosine kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 10
Names
CEA-related cell adhesion molecule 10
carcinoembryonic antigen 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001374785.1 → NP_001361714.1  carcinoembryonic antigen-related cell adhesion molecule 10 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC161488
    Consensus CDS
    CCDS90181.1
    UniProtKB/TrEMBL
    A0A0U1RQ24
    Related
    ENSMUSP00000146217.2, ENSMUST00000206847.2
    Conserved Domains (1) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

  2. NM_007675.4 → NP_031701.3  carcinoembryonic antigen-related cell adhesion molecule 10 isoform 1 precursor

    See identical proteins and their annotated locations for NP_031701.3

    Status: VALIDATED

    Source sequence(s)
    AC161488, AK018529, BE949028
    Consensus CDS
    CCDS39833.1
    UniProtKB/Swiss-Prot
    Q61400, Q99LD6, Q9D329
    UniProtKB/TrEMBL
    A0A0R4J0G1
    Related
    ENSMUSP00000037036.8, ENSMUST00000038069.9
    Conserved Domains (1) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    24476592..24484081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242605.2 → XP_030098465.1  carcinoembryonic antigen-related cell adhesion molecule 10 isoform X1

    Conserved Domains (1) summary
    cd05774
    Location:32 → 136
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q61400.1 GenPept UniProtKB/Swiss-Prot:Q61400

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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