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Gulo gulonolactone (L-) oxidase [ Mus musculus (house mouse) ]

Gene ID: 268756, updated on 14-Sep-2021

Summary

Official Symbol
Guloprovided by MGI
Official Full Name
gulonolactone (L-) oxidaseprovided by MGI
Primary source
MGI:MGI:1353434
See related
Ensembl:ENSMUSG00000034450
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sf; GLO; LGO; sfx; unh; unhip; AU018375; BC028822; 5730581M22
Expression
Biased expression in liver adult (RPKM 119.3), liver E18 (RPKM 17.3) and 2 other tissues See more
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Genomic context

See Gulo in Genome Data Viewer
Location:
14; 14 D1
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66224235..66246703, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65986786..66009254, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66605624..66628047, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 19222 Neighboring gene clusterin Neighboring gene a disintegrin and metallopeptidase domain 2 Neighboring gene translocase of inner mitochondrial membrane 23 homolog pseudogene Neighboring gene epoxide hydrolase 2, cytoplasmic

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC29968, MGC37793, MGC37880

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables D-arabinono-1,4-lactone oxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables FAD binding IEA
Inferred from Electronic Annotation
more info
 
enables L-gulonolactone oxidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables L-gulonolactone oxidase activity ISO
Inferred from Sequence Orthology
more info
 
enables flavin adenine dinucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
L-gulonolactone oxidase
Names
L-gulono-gamma-lactone oxidase
NP_848862.1
XP_006519129.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178747.3NP_848862.1  L-gulonolactone oxidase

    See identical proteins and their annotated locations for NP_848862.1

    Status: PROVISIONAL

    Source sequence(s)
    AC126444
    Consensus CDS
    CCDS36958.1
    UniProtKB/Swiss-Prot
    P58710
    Related
    ENSMUSP00000060912.8, ENSMUST00000059970.9
    Conserved Domains (1) summary
    TIGR01678
    Location:7433
    FAD_lactone_ox; sugar 1,4-lactone oxidases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    66224235..66246703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519066.1XP_006519129.1  L-gulonolactone oxidase isoform X1

    See identical proteins and their annotated locations for XP_006519129.1

    UniProtKB/Swiss-Prot
    P58710
    Conserved Domains (1) summary
    TIGR01678
    Location:7433
    FAD_lactone_ox; sugar 1,4-lactone oxidases

RNA

  1. XR_001781125.1 RNA Sequence

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