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Nbeal1 neurobeachin like 1 [ Mus musculus (house mouse) ]

Gene ID: 269198, updated on 5-Mar-2024

Summary

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Official Symbol
Nbeal1provided by MGI
Official Full Name
neurobeachin like 1provided by MGI
Primary source
MGI:MGI:2444343
See related
Ensembl:ENSMUSG00000073664 AllianceGenome:MGI:2444343
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ALS2CR17; 2310076G13Rik; A530050O19Rik; A530083I02Rik
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytosol and membrane. Orthologous to human NBEAL1 (neurobeachin like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 3.9), CNS E18 (RPKM 1.7) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 C2; 1 30.46 cM
Exon count:
62
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (60217910..60377487)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (60178740..60338328)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:60154934-60155145 Neighboring gene WD repeat domain 12 Neighboring gene predicted gene 15464 Neighboring gene calcium response factor Neighboring gene STARR-seq mESC enhancer starr_01061 Neighboring gene STARR-positive B cell enhancer mm9_chr1:60297214-60297515 Neighboring gene STARR-seq mESC enhancer starr_01062 Neighboring gene STARR-seq mESC enhancer starr_01063 Neighboring gene protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) pseudogene Neighboring gene STARR-seq mESC enhancer starr_01064 Neighboring gene STARR-seq mESC enhancer starr_01065 Neighboring gene cytochrome P450, family 20, subfamily a, polypeptide 1 Neighboring gene STARR-seq mESC enhancer starr_01070 Neighboring gene abl interactor 2 Neighboring gene Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
  2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
neurobeachin-like protein 1

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173444.2 → NP_775620.2  neurobeachin-like protein 1

    Status: VALIDATED

    Source sequence(s)
    AC158139, AK040951, AK143706, BC060141, BQ550685
    Consensus CDS
    CCDS48274.1
    UniProtKB/TrEMBL
    E9PYP2
    Related
    ENSMUSP00000124056.2, ENSMUST00000160834.8
    Conserved Domains (6) summary
    cd01201
    Location:1881 → 1978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2439 → 2484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1999 → 2278
    Beach; Beige/BEACH domain
    pfam15787
    Location:859 → 1129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1575 → 1828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2403 → 2676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    60217910..60377487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496030.5 → XP_006496093.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496093.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_006496033.5 → XP_006496096.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496096.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_006496032.5 → XP_006496095.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496095.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_006496035.4 → XP_006496098.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496098.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_030254693.1 → XP_030110553.1  neurobeachin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    E9PYP2
    Conserved Domains (6) summary
    cd01201
    Location:1881 → 1978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2439 → 2484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1999 → 2278
    Beach; Beige/BEACH domain
    pfam15787
    Location:859 → 1129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1575 → 1828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2403 → 2676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_006496038.5 → XP_006496101.1  neurobeachin-like protein 1 isoform X5

    Conserved Domains (3) summary
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    pfam15787
    Location:888 → 1158
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)

  7. XM_030254697.2 → XP_030110557.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:1731 → 1828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2289 → 2334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1849 → 2128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709 → 979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1425 → 1678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2253 → 2526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  8. XM_011238527.4 → XP_011236829.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011236829.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_006496037.5 → XP_006496100.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:1731 → 1828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2289 → 2334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1849 → 2128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709 → 979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1425 → 1678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2253 → 2526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  10. XM_030254700.2 → XP_030110560.1  neurobeachin-like protein 1 isoform X4

    Conserved Domains (6) summary
    cd01201
    Location:1702 → 1799
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2260 → 2305
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1820 → 2099
    Beach; Beige/BEACH domain
    pfam15787
    Location:680 → 950
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1396 → 1649
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2224 → 2497
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  11. XM_006496029.4 → XP_006496092.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496092.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  12. XM_006496034.4 → XP_006496097.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496097.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  13. XM_030254692.2 → XP_030110552.1  neurobeachin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    E9PYP2
    Conserved Domains (6) summary
    cd01201
    Location:1881 → 1978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2439 → 2484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1999 → 2278
    Beach; Beige/BEACH domain
    pfam15787
    Location:859 → 1129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1575 → 1828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2403 → 2676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  14. XM_030254694.2 → XP_030110554.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:1731 → 1828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2289 → 2334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1849 → 2128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709 → 979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1425 → 1678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2253 → 2526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  15. XM_030254696.2 → XP_030110556.1  neurobeachin-like protein 1 isoform X3

    Conserved Domains (6) summary
    cd01201
    Location:1731 → 1828
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2289 → 2334
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1849 → 2128
    Beach; Beige/BEACH domain
    pfam15787
    Location:709 → 979
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1425 → 1678
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2253 → 2526
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  16. XM_006496028.5 → XP_006496091.1  neurobeachin-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496091.1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  17. XM_030254689.2 → XP_030110549.1  neurobeachin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    E9PYP2
    Conserved Domains (6) summary
    cd01201
    Location:1881 → 1978
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2439 → 2484
    7WD40; WD40 repeat [structural motif]
    pfam02138
    Location:1999 → 2278
    Beach; Beige/BEACH domain
    pfam15787
    Location:859 → 1129
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1575 → 1828
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2403 → 2676
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  18. XM_036165459.1 → XP_036021352.1  neurobeachin-like protein 1 isoform X1

    Conserved Domains (6) summary
    smart01026
    Location:2027 → 2307
    Beach; Beige/BEACH domain
    cd01201
    Location:1910 → 2007
    PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
    sd00039
    Location:2468 → 2513
    7WD40; WD40 repeat [structural motif]
    pfam15787
    Location:888 → 1152
    DUF4704; Domain of unknown function (DUF4704)
    pfam16057
    Location:1604 → 1857
    DUF4800; Domain of unknown function (DUF4800)
    cl29593
    Location:2432 → 2705
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

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