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Luzp1 leucine zipper protein 1 [ Mus musculus (house mouse) ]

Gene ID: 269593, updated on 24-Apr-2022

Summary

Official Symbol
Luzp1provided by MGI
Official Full Name
leucine zipper protein 1provided by MGI
Primary source
MGI:MGI:107629
See related
Ensembl:ENSMUSG00000001089 AllianceGenome:MGI:107629
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Luzp; AI266952; mFLJ00226; 2700072H04Rik
Summary
Acts upstream of or within artery development; neural fold bending; and ventricular septum development. Located in nucleus. Is expressed in several structures, including alimentary system; brain; lung; pharyngo-tympanic tube; and skin. Orthologous to human LUZP1 (leucine zipper protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 24.4), cerebellum adult (RPKM 11.9) and 28 other tissues See more
Orthologs
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Genomic context

See Luzp1 in Genome Data Viewer
Location:
4 D3; 4 68.8 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (136189892..136282036)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (136462609..136554725)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (136025676..136105233)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31295 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 1D Neighboring gene lysine (K)-specific demethylase 1A Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene testis expressed 46 Neighboring gene lactamase, beta-like 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC169408, MGC169410

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within artery development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neural fold bending IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within neural fold bending IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within ventricular septum development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
leucine zipper protein 1
Names
leucine zipper motif-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024452.2NP_077772.2  leucine zipper protein 1

    See identical proteins and their annotated locations for NP_077772.2

    Status: VALIDATED

    Source sequence(s)
    AK139583, AL671173
    Consensus CDS
    CCDS38923.1
    UniProtKB/Swiss-Prot
    Q8R4U7
    Related
    ENSMUSP00000130758.2, ENSMUST00000170102.8
    Conserved Domains (1) summary
    COG1196
    Location:19354
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    136189892..136282036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253587.2XP_030109447.1  leucine zipper protein 1 isoform X1

    Conserved Domains (1) summary
    COG1196
    Location:19354
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_006538921.3XP_006538984.1  leucine zipper protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006538984.1

    UniProtKB/Swiss-Prot
    Q8R4U7
    Related
    ENSMUSP00000101475.3, ENSMUST00000105849.9
    Conserved Domains (1) summary
    COG1196
    Location:19354
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_030253588.1XP_030109448.1  leucine zipper protein 1 isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:19354
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_390755.2 RNA Sequence

  2. XR_390753.2 RNA Sequence