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Mon1b MON1 homolog B, secretory traffciking associated [ Mus musculus (house mouse) ]

Gene ID: 270096, updated on 5-Mar-2024

Summary

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Official Symbol
Mon1bprovided by MGI
Official Full Name
MON1 homolog B, secretory traffciking associatedprovided by MGI
Primary source
MGI:MGI:1923231
See related
Ensembl:ENSMUSG00000078908 AllianceGenome:MGI:1923231
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5031407H10; 5033413H12Rik
Summary
Predicted to be involved in early viral transcription and late viral transcription. Predicted to be located in cytoplasm. Predicted to be part of Mon1-Ccz1 complex. Orthologous to human MON1B (MON1 homolog B, secretory trafficking associated). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 6.2), adrenal adult (RPKM 5.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 E1; 8 59.65 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (114362218..114371824)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (113635586..113645192)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930571O06 gene Neighboring gene predicted gene, 24291 Neighboring gene STARR-seq mESC enhancer starr_22761 Neighboring gene collagen, type III, alpha 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_22762 Neighboring gene STARR-positive B cell enhancer ABC_E1771 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:116159691-116159874 Neighboring gene synaptonemal complex central element protein 1 like Neighboring gene predicted gene, 30052 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells. Kinchen JM, et al. Nature, 2010 Apr 1. PMID 20305638, Free PMC Article
  2. A molecular profile of a hematopoietic stem cell niche. Hackney JA, et al. Proc Natl Acad Sci U S A, 2002 Oct 1. PMID 12226475, Free PMC Article
  3. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in early viral transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in late viral transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in protein targeting to vacuole IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Mon1-Ccz1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mon1-Ccz1 complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
vacuolar fusion protein MON1 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048143.2 → NP_001041608.1  vacuolar fusion protein MON1 homolog B

    See identical proteins and their annotated locations for NP_001041608.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC125463, BC062639, CJ089261
    Consensus CDS
    CCDS22685.1
    UniProtKB/Swiss-Prot
    Q69ZX1, Q6P5V5, Q8BMQ8
    Related
    ENSMUSP00000137605.2, ENSMUST00000179926.9
    Conserved Domains (1) summary
    pfam03164
    Location:114 → 531
    Mon1; Trafficking protein Mon1

  2. NM_173015.3 → NP_766603.1  vacuolar fusion protein MON1 homolog B

    See identical proteins and their annotated locations for NP_766603.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC125463, AK030288, BC062639, BY742778
    Consensus CDS
    CCDS22685.1
    UniProtKB/Swiss-Prot
    Q69ZX1, Q6P5V5, Q8BMQ8
    Related
    ENSMUSP00000045089.9, ENSMUST00000035777.10
    Conserved Domains (1) summary
    pfam03164
    Location:114 → 531
    Mon1; Trafficking protein Mon1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    114362218..114371824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BMQ8.1 GenPept UniProtKB/Swiss-Prot:Q8BMQ8

Gene LinkOut

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