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Klhdc1 kelch domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 271005, updated on 8-Jul-2021

Summary

Official Symbol
Klhdc1provided by MGI
Official Full Name
kelch domain containing 1provided by MGI
Primary source
MGI:MGI:2672853
See related
Ensembl:ENSMUSG00000051890
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Broad expression in testis adult (RPKM 2.2), frontal lobe adult (RPKM 2.0) and 25 other tissues See more
Orthologs
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Genomic context

See Klhdc1 in Genome Data Viewer
Location:
12; 12 C2
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (69274529..69331420)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (69227729..69284646)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (70342819..70384948)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9330151L19 gene Neighboring gene mannoside acetylglucosaminyltransferase 2 Neighboring gene dynein, axonemal assembly factor 2 Neighboring gene polymerase (DNA directed), epsilon 2 (p59 subunit) Neighboring gene kelch domain containing 2 Neighboring gene nuclear export mediator factor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Homology

Clone Names

  • MGC141300, MGC141301

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin ligase-substrate adaptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of Cul5-RING ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
kelch domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178253.5NP_839984.1  kelch domain-containing protein 1

    See identical proteins and their annotated locations for NP_839984.1

    Status: PROVISIONAL

    Source sequence(s)
    AC099934
    Consensus CDS
    CCDS25949.1
    UniProtKB/Swiss-Prot
    Q80YG3
    Related
    ENSMUSP00000068046.7, ENSMUST00000063445.13
    Conserved Domains (4) summary
    sd00038
    Location:197245
    Kelch; KELCH repeat [structural motif]
    pfam13415
    Location:206256
    Kelch_3; Galactose oxidase, central domain
    pfam13418
    Location:247295
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:1354
    Kelch_5; Kelch motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    69274529..69331420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244119.4XP_011242421.1  kelch domain-containing protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011242421.1

    Conserved Domains (3) summary
    PLN02153
    Location:138278
    PLN02153; epithiospecifier protein
    PLN02193
    Location:1237
    PLN02193; nitrile-specifier protein
    sd00038
    Location:152200
    Kelch; KELCH repeat [structural motif]
  2. XM_011244121.4XP_011242423.1  kelch domain-containing protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011242423.1

    Conserved Domains (3) summary
    PLN02153
    Location:138278
    PLN02153; epithiospecifier protein
    PLN02193
    Location:1237
    PLN02193; nitrile-specifier protein
    sd00038
    Location:152200
    Kelch; KELCH repeat [structural motif]
  3. XM_011244120.2XP_011242422.1  kelch domain-containing protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011242422.1

    Conserved Domains (3) summary
    PLN02153
    Location:138278
    PLN02153; epithiospecifier protein
    PLN02193
    Location:1237
    PLN02193; nitrile-specifier protein
    sd00038
    Location:152200
    Kelch; KELCH repeat [structural motif]
  4. XM_036157435.1XP_036013328.1  kelch domain-containing protein 1 isoform X1

    Conserved Domains (3) summary
    PHA03098
    Location:13162
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:1365
    Kelch; KELCH repeat [structural motif]
    pfam13418
    Location:219267
    Kelch_4; Galactose oxidase, central domain
  5. XM_030246743.1XP_030102603.1  kelch domain-containing protein 1 isoform X3

    Conserved Domains (2) summary
    PLN02153
    Location:62202
    PLN02153; epithiospecifier protein
    sd00038
    Location:76124
    Kelch; KELCH repeat [structural motif]
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