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A3303_gp480 dihydrofolate reductase [ Brazilian marseillevirus ]

Gene ID: 27112393, updated on 9-Jan-2023

Summary

Gene symbol
A3303_gp480
Gene description
dihydrofolate reductase
Locus tag
A3303_gp480
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Brazilian marseillevirus (strain: BH2014, acronym: BrMV, nat-host: Acanthamoeba castellanii)
Lineage
Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes; Pimascovirales; Marseilleviridae; Marseillevirus
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Genomic context

Sequence:
NC_029692.1 (352021..353361, complement)

NC_029692.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

General protein information

Preferred Names
dihydrofolate reductase
YP_009238985.1
  • ORF_L480

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_029692.1 Reference assembly

    Range
    352021..353361 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009238985.1 dihydrofolate reductase [Brazilian marseillevirus]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A142CKM6
    Conserved Domains (3) summary
    PTZ00164
    Location:6446
    PTZ00164; bifunctional dihydrofolate reductase-thymidylate synthase; Provisional
    pfam00303
    Location:164446
    Thymidylat_synt; Thymidylate synthase
    cl17279
    Location:6132
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...