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Adcy10 adenylate cyclase 10 [ Mus musculus (house mouse) ]

Gene ID: 271639, updated on 23-Jun-2021

Summary

Official Symbol
Adcy10provided by MGI
Official Full Name
adenylate cyclase 10provided by MGI
Primary source
MGI:MGI:2660854
See related
Ensembl:ENSMUSG00000026567
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
s; Sa; sAC; Sacy; 4931412F17; 4930431D04Rik
Expression
Restricted expression toward testis adult (RPKM 24.0) See more
Orthologs
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Genomic context

See Adcy10 in Genome Data Viewer
Location:
1; 1 H2.3
Exon count:
35
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (165309114..165404347)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (165483518..165576778)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (167415314..167506904)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 6 Neighboring gene predicted gene, 24637 Neighboring gene mitochondrial pyruvate carrier 2 Neighboring gene peptidylprolyl isomerase A pseudogene 1_1625.1 Neighboring gene zinc finger protein 758 pseudogene Neighboring gene predicted gene, 51751 Neighboring gene predicted gene, 51750 Neighboring gene myelin protein zero-like 1 Neighboring gene nuclear encoded tRNA proline 2 (anticodon AGG)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
 
enables adenylate cyclase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables adenylate cyclase activity ISO
Inferred from Sequence Orthology
more info
 
enables adenylate cyclase activity TAS
Traceable Author Statement
more info
PubMed 
enables bicarbonate binding ISO
Inferred from Sequence Orthology
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables manganese ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cAMP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to inorganic substance ISO
Inferred from Sequence Orthology
more info
 
involved_in cyclic nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in epithelial cilium movement involved in extracellular fluid movement ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in apical part of cell ISO
Inferred from Sequence Orthology
more info
 
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in axon ISO
Inferred from Sequence Orthology
more info
 
located_in basal part of cell ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm TAS
Traceable Author Statement
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with motile cilium ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adenylate cyclase type 10
Names
germ cell soluble adenylyl cyclase
testicular soluble adenylyl cyclase
NP_001344356.1
NP_766617.2
XP_006496930.1
XP_011237125.1
XP_017176545.1
XP_017176549.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357427.1NP_001344356.1  adenylate cyclase type 10 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC102776, AC162789
  2. NM_173029.3NP_766617.2  adenylate cyclase type 10 isoform 1

    See identical proteins and their annotated locations for NP_766617.2

    Status: VALIDATED

    Source sequence(s)
    AK029849, BC138448
    Consensus CDS
    CCDS35756.1
    UniProtKB/Swiss-Prot
    Q8C0T9
    Related
    ENSMUSP00000027852.9, ENSMUST00000027852.15
    Conserved Domains (2) summary
    cd07302
    Location:40214
    CHD; cyclase homology domain
    COG3899
    Location:485959
    COG3899; Predicted ATPase [General function prediction only]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    165309114..165404347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321056.3XP_017176545.1  adenylate cyclase type 10 isoform X1

    UniProtKB/Swiss-Prot
    Q8C0T9
    Conserved Domains (2) summary
    cd07302
    Location:40214
    CHD; cyclase homology domain
    COG3899
    Location:485959
    COG3899; Predicted ATPase [General function prediction only]
  2. XM_017321060.2XP_017176549.1  adenylate cyclase type 10 isoform X2

    UniProtKB/TrEMBL
    E9Q9T4
    Related
    ENSMUSP00000107066.2, ENSMUST00000111439.8
    Conserved Domains (2) summary
    cd07302
    Location:40214
    CHD; cyclase homology domain
    COG3899
    Location:485959
    COG3899; Predicted ATPase [General function prediction only]
  3. XM_006496867.1XP_006496930.1  adenylate cyclase type 10 isoform X1

    See identical proteins and their annotated locations for XP_006496930.1

    UniProtKB/Swiss-Prot
    Q8C0T9
    Conserved Domains (2) summary
    cd07302
    Location:40214
    CHD; cyclase homology domain
    COG3899
    Location:485959
    COG3899; Predicted ATPase [General function prediction only]
  4. XM_011238823.3XP_011237125.1  adenylate cyclase type 10 isoform X3

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