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Spib Spi-B transcription factor (Spi-1/PU.1 related) [ Mus musculus (house mouse) ]

Gene ID: 272382, updated on 17-Aug-2021

Summary

Official Symbol
Spibprovided by MGI
Official Full Name
Spi-B transcription factor (Spi-1/PU.1 related)provided by MGI
Primary source
MGI:MGI:892986
See related
Ensembl:ENSMUSG00000008193
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sp; Spi-B
Expression
Biased expression in spleen adult (RPKM 101.9), mammary gland adult (RPKM 21.1) and 2 other tissues See more
Orthologs
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Genomic context

See Spib in Genome Data Viewer
Location:
7 B3; 7 28.83 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44175419..44181511, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (44525995..44532087, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (51781365..51787441, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ER membrane protein complex subunit 10 Neighboring gene family with sequence similarity 71, member E1 Neighboring gene myosin binding protein C, fast-type Neighboring gene polymerase (DNA directed), delta 1, catalytic subunit Neighboring gene microRNA 7053 Neighboring gene nuclear receptor subfamily 1, group H, member 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of transcription regulator complex IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
transcription factor Spi-B
Names
Ets transcription factor Spi-B
Spi-1/PU.1 related

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019866.1NP_063919.1  transcription factor Spi-B

    See identical proteins and their annotated locations for NP_063919.1

    Status: VALIDATED

    Source sequence(s)
    CAAA01070168
    Consensus CDS
    CCDS21209.1
    UniProtKB/Swiss-Prot
    O35906
    Related
    ENSMUSP00000035539.5, ENSMUST00000035323.6
    Conserved Domains (1) summary
    smart00413
    Location:173261
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    44175419..44181511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242628.1XP_030098488.1  transcription factor Spi-B isoform X7

    Conserved Domains (1) summary
    smart00413
    Location:155243
    ETS; erythroblast transformation specific domain
  2. XM_006540939.3XP_006541002.1  transcription factor Spi-B isoform X9

  3. XM_006540933.3XP_006540996.1  transcription factor Spi-B isoform X2

    UniProtKB/Swiss-Prot
    O35906
    Related
    ENSMUSP00000096084.4, ENSMUST00000098483.9
    Conserved Domains (1) summary
    smart00413
    Location:191279
    ETS; erythroblast transformation specific domain
  4. XM_006540938.4XP_006541001.1  transcription factor Spi-B isoform X8

  5. XM_006540934.4XP_006540997.1  transcription factor Spi-B isoform X4

    Conserved Domains (1) summary
    smart00413
    Location:174262
    ETS; erythroblast transformation specific domain
  6. XM_006540932.5XP_006540995.1  transcription factor Spi-B isoform X1

    Conserved Domains (1) summary
    smart00413
    Location:192280
    ETS; erythroblast transformation specific domain
  7. XM_030242627.2XP_030098487.1  transcription factor Spi-B isoform X6

    Conserved Domains (1) summary
    smart00413
    Location:156244
    ETS; erythroblast transformation specific domain
  8. XM_006540935.5XP_006540998.1  transcription factor Spi-B isoform X3

    UniProtKB/Swiss-Prot
    O35906
    Related
    ENSMUSP00000145968.2, ENSMUST00000205506.2
    Conserved Domains (1) summary
    smart00413
    Location:174262
    ETS; erythroblast transformation specific domain
  9. XM_006540936.4XP_006540999.1  transcription factor Spi-B isoform X5

    Conserved Domains (1) summary
    smart00413
    Location:164252
    ETS; erythroblast transformation specific domain
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