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Defb3 defensin beta 3 [ Mus musculus (house mouse) ]

Gene ID: 27358, updated on 23-Jun-2021

Summary

Official Symbol
Defb3provided by MGI
Official Full Name
defensin beta 3provided by MGI
Primary source
MGI:MGI:1351612
See related
Ensembl:ENSMUSG00000039775
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BD-3
Expression
Low expression observed in reference dataset See more
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Genomic context

See Defb3 in Genome Data Viewer
Location:
8; 8 A1.3
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (19343377..19345355)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (19293361..19295339)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (19293361..19295339)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene defensin beta 46 Neighboring gene defensin beta 5 Neighboring gene defensin, alpha, pseudogene 13 Neighboring gene defensin, alpha, pseudogene 14

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Clone Names

  • MGC129397

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables CCR6 chemokine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chemoattractant activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cell chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within defense response IEA
Inferred from Electronic Annotation
more info
 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013756.2NP_038784.1  beta-defensin 3 precursor

    See identical proteins and their annotated locations for NP_038784.1

    Status: VALIDATED

    Source sequence(s)
    AC113099, AF092929
    Consensus CDS
    CCDS40258.1
    UniProtKB/Swiss-Prot
    Q9WTL0
    Related
    ENSMUSP00000033852.8, ENSMUST00000033852.8
    Conserved Domains (1) summary
    pfam00711
    Location:2861
    Defensin_beta; Beta defensin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    19343377..19345355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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