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Rai1 Rat1 Interacting Protein 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768882, updated on 26-Apr-2024

Summary

Official Symbol
Rai1provided by FlyBase
Official Full Name
Rat1 Interacting Protein 1provided by FlyBase
Primary source
FLYBASE:FBgn0030793
Locus tag
Dmel_CG9125
See related
AllianceGenome:FB:FBgn0030793
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32566; CG9125; Dmel\CG9125; dRai1
Summary
Enables 5'-3' exoribonuclease activity and RNA pyrophosphohydrolase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be active in cytosol and nucleus. Is expressed in spermatozoon. Orthologous to human DXO (decapping exoribonuclease). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:
15A9-15A9; 1-55 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16801929..16803344, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16695962..16697377, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene SIN3-associated polypeptide 30 Neighboring gene Rrp45 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44053 Neighboring gene pickpocket 28

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 5'-3' RNA exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA 5'-diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA 5'-diphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in NAD-cap decapping IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in nuclear-transcribed mRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Rat1 interacting protein 1
Names
CG9125-PA
Rai1-PA
NP_996492.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    16801929..16803344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206769.3NP_996492.1  Rat1 interacting protein 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996492.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VXA8
    UniProtKB/TrEMBL
    B4F5G7, B4F5G8
    Conserved Domains (1) summary
    pfam08652
    Location:224296
    RAI1; RAI1 like PD-(D/E)XK nuclease