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Vsig4 V-set and immunoglobulin domain containing 4 [ Mus musculus (house mouse) ]

Gene ID: 278180, updated on 5-Jan-2022

Summary

Official Symbol
Vsig4provided by MGI
Official Full Name
V-set and immunoglobulin domain containing 4provided by MGI
Primary source
MGI:MGI:2679720
See related
Ensembl:ENSMUSG00000044206
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CRIg; Z39IG; BC025105; A530061A11
Summary
Predicted to enable complement component C3b binding activity. Acts upstream of or within negative regulation of T cell proliferation and negative regulation of interleukin-2 production. Predicted to be part of protein-containing complex. Is expressed in bone marrow; oviduct; and thyroid gland. Orthologous to human VSIG4 (V-set and immunoglobulin domain containing 4). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in liver E18 (RPKM 5.0), liver adult (RPKM 2.5) and 1 other tissue See more
Orthologs
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Genomic context

See Vsig4 in Genome Data Viewer
Location:
X; X C3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (95290807..95337044, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (96247201..96293438, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (93442542..93488777, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA F630028O10 gene Neighboring gene solute carrier family 37 (glycerol-3-phosphate transporter), member 3 pseudogene Neighboring gene microRNA 223 Neighboring gene predicted gene, 18171 Neighboring gene heat shock transcription factor 3 Neighboring gene cofilin 1, non-muscle pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Homology

Clone Names

  • MGC36211

General protein information

Preferred Names
V-set and immunoglobulin domain-containing protein 4
Names
complement receptor of the immunoglobulin superfamily

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177789.5NP_808457.1  V-set and immunoglobulin domain-containing protein 4 precursor

    See identical proteins and their annotated locations for NP_808457.1

    Status: VALIDATED

    Source sequence(s)
    AL831708
    Consensus CDS
    CCDS30288.1
    UniProtKB/TrEMBL
    F6TUL9
    Related
    ENSMUSP00000051521.2, ENSMUST00000050707.3
    Conserved Domains (1) summary
    cl11960
    Location:35136
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    95290807..95337044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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