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ACO2 aconitase 2 [ Bos taurus (cattle) ]

Gene ID: 280976, updated on 14-Jan-2019

Summary

Official Symbol
ACO2provided by VGNC
Official Full Name
aconitase 2provided by VGNC
Primary source
VGNC:VGNC:25546
See related
BGD:BT23912; Ensembl:ENSBTAG00000006429
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See ACO2 in Genome Data Viewer
Location:
5q35
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 5 NC_037332.1 (112568137..112617183)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 5 AC_000162.1 (113089139..113138185)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene transducer of ERBB2, 2 Neighboring gene PHD finger protein 5A Neighboring gene small nucleolar RNA SNORA11 Neighboring gene RNA polymerase III subunit H Neighboring gene transfer RNA methionine (anticodon CAU) Neighboring gene cold shock domain containing C2

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
3 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
aconitate hydratase activity IDA
Inferred from Direct Assay
more info
PubMed 
aconitate hydratase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
ferrous iron binding IDA
Inferred from Direct Assay
more info
PubMed 
iron ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
citrate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
citrate metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
tricarboxylic acid cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
aconitate hydratase, mitochondrial
Names
aconitase 2, mitochondrial
citrate hydro-lyase
NP_776402.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173977.3NP_776402.1  aconitate hydratase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_776402.1

    Status: PROVISIONAL

    Source sequence(s)
    Z49931
    UniProtKB/Swiss-Prot
    P20004
    Related
    ENSBTAP00000008431.4, ENSBTAT00000008431.5
    Conserved Domains (3) summary
    cd01584
    Location:95505
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:587735
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:45775
    aconitase_mito; aconitate hydratase, mitochondrial

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    112568137..112617183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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