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CD36 CD36 molecule (CD36 blood group) [ Bos taurus (cattle) ]

Gene ID: 281052, updated on 3-Apr-2024

Summary

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Gene symbol
CD36
Gene description
CD36 molecule (CD36 blood group)
See related
BGD:BT10335; Ensembl:ENSBTAG00000017866
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
GPIV; PAS-4; GPIIIB
Orthologs
human mouse all
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Genomic context

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See CD36 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (40380301..40474070, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene platelet glycoprotein 4-like Neighboring gene CD36 molecule (thrombospondin receptor) Neighboring gene G protein subunit alpha transducin 3 Neighboring gene cullin-1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. LTA recognition by bovine gammadelta T cells involves CD36. Lubick K, et al. J Leukoc Biol, 2006 Jun. PMID 16551677
  2. Assignment of disulfide bridges in bovine CD36. Rasmussen JT, et al. Eur J Biochem, 1998 Oct 15. PMID 9826197
  3. PAS IV, an integral membrane protein of mammary epithelial cells, is related to platelet and endothelial cell CD36 (GP IV). Greenwalt DE, et al. Biochemistry, 1990 Jul 31. PMID 1699598
  4. Structural, functional, and antigenic differences between bovine heart endothelial CD36 and human platelet CD36. Greenwalt DE, et al. J Biol Chem, 1990 Sep 25. PMID 1697855
  5. Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression. Prodanović R, et al. Res Vet Sci, 2016 Aug. PMID 27473969

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables low-density lipoprotein particle binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables low-density lipoprotein particle receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables scavenger receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta clearance by cellular catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid storage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipoprotein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-chain fatty acid import into cell IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in low-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in caveola IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
platelet glycoprotein 4
Names
CD36 antigen
cluster of differentiation 36
collagen type I receptor, thrombospondin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278621.1 → NP_001265550.1  platelet glycoprotein 4

    See identical proteins and their annotated locations for NP_001265550.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) resents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC103112, DV801272, NKLS02000004
    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  2. NM_174010.3 → NP_776435.2  platelet glycoprotein 4

    See identical proteins and their annotated locations for NP_776435.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC103112, DV842657, NKLS02000004
    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    40380301..40474070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059885384.1 → XP_059741367.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  2. XM_059885382.1 → XP_059741365.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  3. XM_005205326.5 → XP_005205383.1  platelet glycoprotein 4 isoform X1

    See identical proteins and their annotated locations for XP_005205383.1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Related
    ENSBTAP00000023750.5, ENSBTAT00000023750.7
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  4. XM_015468818.3 → XP_015324304.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  5. XM_024990428.2 → XP_024846196.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  6. XM_059885388.1 → XP_059741371.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  7. XM_059885389.1 → XP_059741372.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  8. XM_024990418.2 → XP_024846186.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  9. XM_059885381.1 → XP_059741364.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  10. XM_024990431.2 → XP_024846199.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  11. XM_015468812.3 → XP_015324298.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  12. XM_024990427.2 → XP_024846195.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  13. XM_024990421.2 → XP_024846189.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  14. XM_024990433.2 → XP_024846201.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  15. XM_024990419.2 → XP_024846187.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  16. XM_024990429.2 → XP_024846197.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  17. XM_059885383.1 → XP_059741366.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  18. XM_024990434.2 → XP_024846202.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  19. XM_059885386.1 → XP_059741369.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  20. XM_024990417.2 → XP_024846185.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  21. XM_024990430.2 → XP_024846198.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  22. XM_015468815.3 → XP_015324301.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
    UniProtKB/TrEMBL
    G3MY21
    Conserved Domains (1) summary
    pfam01130
    Location:16 → 461
    CD36; CD36 family

  23. XM_059885387.1 → XP_059741370.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7

  24. XM_059885385.1 → XP_059741368.1  platelet glycoprotein 4 isoform X1

    UniProtKB/Swiss-Prot
    P26201, P79111, Q28154, Q3ZBT7
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26201.5 GenPept UniProtKB/Swiss-Prot:P26201

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