CELA3B chymotrypsin-like elastase family, member 3B [Bos taurus (cattle)] - Gene

Summary

Gene symbol: CELA3B
Gene description: chymotrypsin-like elastase family, member 3B
See related: BGD:BT26190; Ensembl:ENSBTAG00000013085
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: ELA3B
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Genomic context

Location:: chromosome: 2

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (130816944..130824150, complement)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: proproteinase E

Names: PROCPA-S6 III; elastase 3B, pancreatic; procarboxypeptidase A complex component III; procarboxypeptidase A-S6 subunit III

NP_001159990.3

EC 3.4.21.70

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001166518.3 → NP_001159990.3 proproteinase E precursor

Status: PROVISIONAL

Source sequence(s)

NKLS02000002

UniProtKB/TrEMBL

F1MSF5, Q95KW7

Related

ENSBTAP00000017401.6, ENSBTAT00000017401.6

Conserved Domains (1) summary

cd00190
Location:29 → 266

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...