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AP2B1 adaptor related protein complex 2 subunit beta 1 [ Bos taurus (cattle) ]

Gene ID: 282183, updated on 3-Apr-2024

Summary

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Official Symbol
AP2B1provided by VGNC
Official Full Name
adaptor related protein complex 2 subunit beta 1provided by VGNC
Primary source
VGNC:VGNC:55033
See related
BGD:BT11432; Ensembl:ENSBTAG00000020316
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
CLAPB1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (14649514..14763818, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343014 Neighboring gene growth arrest specific 2 like 2 Neighboring gene RAS like family 10 member B Neighboring gene Z30 small nucleolar RNA Neighboring gene peroxisomal biogenesis factor 12

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conservation and diversity in families of coated vesicle adaptins. Ponnambalam S, et al. J Biol Chem, 1990 Mar 25. PMID 1969413
  2. Quantitative analysis of TIP47-receptor cytoplasmic domain interactions: implications for endosome-to-trans Golgi network trafficking. Krise JP, et al. J Biol Chem, 2000 Aug 18. PMID 10829017
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables clathrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of clathrin adaptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of membrane coat IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
AP-2 complex subunit beta
Names
AP-1 complex subunit beta-1
AP105B
adapter-related protein complex 1 subunit beta-1
adapter-related protein complex 2 beta subunit
adapter-related protein complex 2 subunit beta
adaptor protein complex AP-1 subunit beta-1
adaptor protein complex AP-2 subunit beta
adaptor-related protein complex 1 subunit beta-1
adaptor-related protein complex 2 subunit beta
adaptor-related protein complex 2, beta 1 subunit
beta-1-adaptin
beta-2-adaptin
beta-adaptin 1
beta1-adaptin
beta2-adaptin
clathrin assembly protein complex 1 beta large chain
clathrin assembly protein complex 2 beta large chain
clathrin-associated / assembly / adaptor protein, large, beta 1
golgi adaptor HA1/AP1 adaptin beta subunit
plasma membrane adaptor HA2/AP2 adaptin beta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075125.2 → NP_001068593.1  AP-2 complex subunit beta

    See identical proteins and their annotated locations for NP_001068593.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123583
    UniProtKB/Swiss-Prot
    Q08DS7
    Related
    ENSBTAP00000060816.1, ENSBTAT00000076585.2
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    14649514..14763818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059877728.1 → XP_059733711.1  AP-2 complex subunit beta isoform X2

    UniProtKB/Swiss-Prot
    P63009

  2. XM_059877727.1 → XP_059733710.1  AP-2 complex subunit beta isoform X1

    UniProtKB/Swiss-Prot
    Q08DS7

  3. XM_024979626.2 → XP_024835394.1  AP-2 complex subunit beta isoform X2

    UniProtKB/Swiss-Prot
    P63009
    UniProtKB/TrEMBL
    G3X7G4
    Related
    ENSBTAP00000027078.7, ENSBTAT00000027078.7
    Conserved Domains (4) summary
    smart00809
    Location:717 → 817
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:826 → 936
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  4. XM_024979622.2 → XP_024835390.1  AP-2 complex subunit beta isoform X1

    UniProtKB/Swiss-Prot
    Q08DS7
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  5. XM_024979621.2 → XP_024835389.1  AP-2 complex subunit beta isoform X1

    UniProtKB/Swiss-Prot
    Q08DS7
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  6. XM_024979623.2 → XP_024835391.1  AP-2 complex subunit beta isoform X1

    UniProtKB/Swiss-Prot
    Q08DS7
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P63009.2 GenPept UniProtKB/Swiss-Prot:P63009
Q08DS7.1 GenPept UniProtKB/Swiss-Prot:Q08DS7

Gene LinkOut

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