BOLA-DQA5 major histocompatibility complex, class II, DQ alpha 5 [Bos taurus (cattle)] - Gene

Summary

Gene symbol: BOLA-DQA5
Gene description: major histocompatibility complex, class II, DQ alpha 5
See related: BGD:BT10938; Ensembl:ENSBTAG00000038128
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: BoLA-DQA
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 23

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	23	NC_037350.1 (25631958..25643878, complement)

Chromosome 23 - NC_037350.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MHC class II protein complex binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immunoglobulin production involved in immunoglobulin-mediated immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptide antigen assembly with MHC class II protein complex	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell activation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of MHC class II protein complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: major histocompatibility complex, class II, DQ alpha 5

Names: MHC class II antigen

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012675.2 → NP_001012693.2 major histocompatibility complex, class II, DQ alpha 5 precursor

See identical proteins and their annotated locations for NP_001012693.2

Status: VALIDATED

Source sequence(s)

EE251935, EV614021, EV733097

UniProtKB/TrEMBL

A5PJ88, F1N0X9

Conserved Domains (3) summary

cd05767
Location:112 → 205

IgC_MHC_II_alpha; Class II major histocompatibility complex (MHC) alpha chain immunoglobulin domain

pfam00993
Location:30 → 108

MHC_II_alpha; Class II histocompatibility antigen, alpha domain

pfam16196
Location:203 → 254

C1-set_C; C1-set C-terminal domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

Range

25631958..25643878 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015459849.3 → XP_015315335.1 major histocompatibility complex, class II, DQ alpha 5 isoform X1

UniProtKB/TrEMBL

A5PJ88, F1N0X9

Related

ENSBTAP00000019800.5, ENSBTAT00000019800.7

Conserved Domains (3) summary

cd05767
Location:112 → 205

IgC_MHC_II_alpha; Class II major histocompatibility complex (MHC) alpha chain immunoglobulin domain

pfam00993
Location:30 → 108

MHC_II_alpha; Class II histocompatibility antigen, alpha domain

pfam16196
Location:203 → 254

C1-set_C; C1-set C-terminal domain
XM_059880217.1 → XP_059736200.1 major histocompatibility complex, class II, DQ alpha 5 isoform X1

UniProtKB/TrEMBL

F1N0X9