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BOLA-DQB major histocompatibility complex, class II, DQ beta [ Bos taurus (cattle) ]

Gene ID: 282495, updated on 16-Jan-2024

Summary

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Gene symbol
BOLA-DQB
Gene description
major histocompatibility complex, class II, DQ beta
See related
BGD:BT10584; Ensembl:ENSBTAG00000021077
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

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Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (25607507..25620857)

Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene ELOVL fatty acid elongase 5 Neighboring gene major histocompatibility complex, class II, DQ alpha 2 Neighboring gene major histocompatibility complex, class II, DQ alpha 5 Neighboring gene MHC class II antigen

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evidence for an additional cattle DQB locus. Gelhaus A, et al. Immunogenetics, 1999 Sep. PMID 10436182
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC class II protein complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunoglobulin production involved in immunoglobulin-mediated immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide antigen assembly with MHC class II protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MHC class II protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
major histocompatibility complex, class II, DQ beta
Names
MHC class II antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012676.3 → NP_001012694.2  major histocompatibility complex, class II, DQ beta precursor

    See identical proteins and their annotated locations for NP_001012694.2

    Status: PROVISIONAL

    Source sequence(s)
    BC133449
    UniProtKB/TrEMBL
    A2VDX2, O98264
    Related
    ENSBTAP00000026100.3, ENSBTAT00000026100.4
    Conserved Domains (2) summary
    cd05766
    Location:129 → 222
    IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain
    pfam00969
    Location:45 → 117
    MHC_II_beta; Class II histocompatibility antigen, beta domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    25607507..25620857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010818288.4 → XP_010816590.1  major histocompatibility complex, class II, DQ beta isoform X1

    UniProtKB/TrEMBL
    G5E552
    Related
    ENSBTAP00000043594.3, ENSBTAT00000046279.4
    Conserved Domains (2) summary
    cd05766
    Location:129 → 222
    IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain
    pfam00969
    Location:45 → 117
    MHC_II_beta; Class II histocompatibility antigen, beta domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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