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Serpinb1-ps1 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene [ Mus musculus (house mouse) ]

Gene ID: 282665, updated on 8-Feb-2024

Summary

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Official Symbol
Serpinb1-ps1provided by MGI
Official Full Name
serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogeneprovided by MGI
Primary source
MGI:MGI:2445366
See related
Ensembl:ENSMUSG00000081433 AllianceGenome:MGI:2445366
Gene type
pseudo
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EID; ovalbumin
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Genomic context

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Location:
13 A3.2; 13 13.76 cM
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (33043931..33047161, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (32859948..32863178, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene Werner helicase interacting protein 1 Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1a Neighboring gene predicted gene, 35899 Neighboring gene nonconserved acetylation island sequence M71 enhancer Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1c Neighboring gene SCAN domain containing 3 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection. Gong D, et al. J Infect Dis, 2011 Aug 15. PMID 21791661, Free PMC Article
  2. SerpinB1 deficiency is not associated with increased susceptibility to pulmonary emphysema in mice. Cremona TP, et al. Am J Physiol Lung Cell Mol Physiol, 2013 Dec. PMID 24163143
  3. SerpinB1 protects the mature neutrophil reserve in the bone marrow. Benarafa C, et al. J Leukoc Biol, 2011 Jul. PMID 21248149, Free PMC Article
  4. The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection. Benarafa C, et al. J Exp Med, 2007 Aug 6. PMID 17664292, Free PMC Article
  5. Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1). Benarafa C, et al. J Biol Chem, 2002 Nov 1. PMID 12189154

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. serpinB1 are similarly potent inhibitors of neutrophil proteases, serpinB1 deficiency is not associated with more severe emphysema
    Title: SerpinB1 deficiency is not associated with increased susceptibility to pulmonary emphysema in mice.
  2. The study highlights the critical role of serpinB1 in mitigating inflammation and restricting pro-inflammatory cytokine production in influenza infection.
    Title: Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection.
  3. serpinB1 sustains a healthy neutrophil reserve that is required in acute immune responses.
    Title: SerpinB1 protects the mature neutrophil reserve in the bone marrow.
  4. serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection
    Title: The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection.
  5. cDNA cloning, gene structure and biological characterization homologous to human MNEI
    Title: Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1).
Submit: New GeneRIF Correction

General gene information

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Other Names

  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1, pseudogene
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1a pseudogene
  • serine (or cysteine) proteinase inhibitor, clade B, member 1, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_003057.2 

    Range
    101..3331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    33043931..33047161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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