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INHBA-AS1 INHBA antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 285954, updated on 10-Oct-2023

Summary

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Official Symbol
INHBA-AS1provided by HGNC
Official Full Name
INHBA antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:40303
See related
Ensembl:ENSG00000224116 AllianceGenome:HGNC:40303
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
7p14.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (41693919..41779378)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (41852317..41937768)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (41733517..41818976)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375247 Neighboring gene uncharacterized LOC107986789 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25899 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:41748736-41749935 Neighboring gene inhibin subunit beta A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25900 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25901 Neighboring gene uncharacterized LOC124901618 Neighboring gene GLI family zinc finger 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:42068797-42069297 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:42105443-42106096 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:42131129-42131824 Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 30

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of lncRNA-associated competing endogenous RNA networks for occurrence and prognosis of gastric carcinoma. Ye L, et al. J Clin Lab Anal, 2021 Dec. PMID 34704289, Free PMC Article
  2. The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG, and CEBPA-AS1 fragments in plasma serve as diagnostic markers for gastric cancer. Ke D, et al. Oncotarget, 2017 Mar 28. PMID 28423525, Free PMC Article
  3. Silencing of long noncoding INHBA antisense RNA1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microRNA-141-3p/myeloid cell leukemia 1 axis. Yang Y, et al. Bioengineered, 2021 Dec. PMID 33977869, Free PMC Article
  4. LncRNA INHBA-AS1 promotes colorectal cancer cell proliferation by sponging miR-422a to increase AKT1 axis. Lin H, et al. Eur Rev Med Pharmacol Sci, 2020 Oct. PMID 33090398
  5. Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition. Zeng Z, et al. J Dent Res, 2013 May. PMID 23470693, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of lncRNA-associated competing endogenous RNA networks for occurrence and prognosis of gastric carcinoma.
    Title: Identification of lncRNA-associated competing endogenous RNA networks for occurrence and prognosis of gastric carcinoma.
  2. Silencing of long noncoding INHBA antisense RNA1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microRNA-141-3p/myeloid cell leukemia 1 axis.
    Title: Silencing of long noncoding INHBA antisense RNA1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microRNA-141-3p/myeloid cell leukemia 1 axis.
  3. LncRNA INHBA-AS1 promotes colorectal cancer cell proliferation by sponging miR-422a to increase AKT1 axis.
    Title: LncRNA INHBA-AS1 promotes colorectal cancer cell proliferation by sponging miR-422a to increase AKT1 axis.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.
EBI GWAS Catalog
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • INHBA antisense RNA 1 (non-protein coding)

Clone Names

  • AC005027.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027118.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents a longer transcript.
    Source sequence(s)
    AC005027
    Related
    ENST00000415848.6

  2. NR_027119.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents a shorter transcript with a distinct terminal exon compared to variant 1.
    Source sequence(s)
    AC005027
    Related
    ENST00000420821.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    41693919..41779378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    41852317..41937768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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