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Dhx40 DEAH-box helicase 40 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287595, updated on 2-May-2024

Summary

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Official Symbol
Dhx40provided by RGD
Official Full Name
DEAH-box helicase 40provided by RGD
Primary source
RGD:1359618
See related
Ensembl:ENSRNOG00000004549 AllianceGenome:RGD:1359618
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA binding activity. Orthologous to human DHX40 (DEAH-box helicase 40). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 218.7), Testes (RPKM 177.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Dhx40 in Genome Data Viewer
Location:
10q26
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (72081867..72118792, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (71584546..71621479, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (74081442..74119032, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene peptidyl-tRNA hydrolase 2 Neighboring gene clathrin heavy chain Neighboring gene uncharacterized LOC120095163 Neighboring gene uncharacterized LOC103693408

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of a novel human DDX40gene, a new member of the DEAH-box protein family. Xu J, et al. J Hum Genet, 2002. PMID 12522690
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC94894

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
probable ATP-dependent RNA helicase DHX40
Names
DEAH (Asp-Glu-Ala-His) box polypeptide 40
DEAH box protein 40
NP_001005873.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005873.1 → NP_001005873.1  probable ATP-dependent RNA helicase DHX40

    See identical proteins and their annotated locations for NP_001005873.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083821
    UniProtKB/Swiss-Prot
    Q5XI69
    UniProtKB/TrEMBL
    A0A8L2RA15, A6HHS1
    Related
    ENSRNOP00000075131.2, ENSRNOT00000085712.2
    Conserved Domains (1) summary
    COG1643
    Location:51 → 750
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    72081867..72118792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XI69.1 GenPept UniProtKB/Swiss-Prot:Q5XI69

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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