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Krt24 keratin 24 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287675, updated on 13-Apr-2024

Summary

Official Symbol
Krt24provided by RGD
Official Full Name
keratin 24provided by RGD
Primary source
RGD:1303157
See related
Ensembl:ENSRNOG00000010970 AllianceGenome:RGD:1303157
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ka24
Summary
Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in intermediate filament-based process. Predicted to be located in keratin filament. Orthologous to human KRT24 (keratin 24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 4.2) See more
Orthologs
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Genomic context

Location:
10q31
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (84728350..84733486, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (84232163..84237299, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (87190184..87195075, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene keratin 222 Neighboring gene uncharacterized LOC134480870 Neighboring gene uncharacterized LOC134480871 Neighboring gene keratin 25 Neighboring gene keratin 26

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament-based process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament TAS
Traceable Author Statement
more info
PubMed 
located_in keratin filament TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
keratin, type I cytoskeletal 24
Names
CK-24
K24
cytokeratin-24
keratin 24, type I
type I keratin KA24
type I keratin-24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004131.2NP_001004131.1  keratin, type I cytoskeletal 24

    See identical proteins and their annotated locations for NP_001004131.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    Q6IFX1
    UniProtKB/TrEMBL
    A6HIX4
    Related
    ENSRNOP00000014851.6, ENSRNOT00000014851.8
    Conserved Domains (1) summary
    pfam00038
    Location:117427
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    84728350..84733486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)